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肠道菌群与非酒精性脂肪性肝炎发生发展的关系

常越 李海

临床肝胆病杂志2018,Vol.34Issue(6):1343-1346,4.
临床肝胆病杂志2018,Vol.34Issue(6):1343-1346,4.DOI:10.3969/j.issn.1001-5256.2018.06.045

肠道菌群与非酒精性脂肪性肝炎发生发展的关系

The role of gut microbiota in the development and progression of nonalcoholic steatohepatitis

常越 1李海1

作者信息

  • 1. 中国人民武装警察部队后勤学院附属医院肝胆胰脾科,天津300162
  • 折叠

摘要

Abstract

Currently, the pathogenesis of nonalcoholic steatohepatitis (NASH) remains unclear, while the theory of "two hits"is insufficient to explain the pathogenesis of NASH in all cases.More and more attention has been paid to the relationship between the change in gut microbio - ta and the development and progression of NASH in recent years .The energy metabolism disorder, lipopolysaccharide endotoxemia, increased endogenous ethanol production, bile acid metabolism disorder, altered choline metabolism, and immune dysfunction caused by gut microbiota are related to NASH.This article reviews the role of gut microbiota in the development and progression of nonalcoholic steatohepatitis .

关键词

肠道菌科/非酒精性脂肪性肝炎/病理过程/综述

Key words

enterobacteriaceae/nonalcoholic steatohepatitis/pathologic processes/review

分类

医药卫生

引用本文复制引用

常越,李海..肠道菌群与非酒精性脂肪性肝炎发生发展的关系[J].临床肝胆病杂志,2018,34(6):1343-1346,4.

临床肝胆病杂志

OA北大核心CSTPCD

1001-5256

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