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辅助性T淋巴细胞17和调节性T淋巴细胞及其平衡改变与非酒精性脂肪性肝病的关系

高伟华 葛宽雪 向晓星

临床肝胆病杂志2018,Vol.34Issue(6):1347-1350,4.
临床肝胆病杂志2018,Vol.34Issue(6):1347-1350,4.DOI:10.3969/j.issn.1001-5256.2018.06.046

辅助性T淋巴细胞17和调节性T淋巴细胞及其平衡改变与非酒精性脂肪性肝病的关系

Association of Th17 cells, regulatory T cells, and their imbalance with nonalcoholic fatty liver disease

高伟华 1葛宽雪 1向晓星2

作者信息

  • 1. 扬州大学医学院,江苏扬州225001
  • 2. 江苏省苏北人民医院,江苏扬州225001
  • 折叠

摘要

Abstract

Nonalcoholic fatty liver disease (NAFLD) is closely associated with insulin resistance and genetic susceptibility and is one of the chronic liver diseases that threaten human health .Under certain conditions, Th17 cells and regulatory T (Treg) cells can be transformed to each other to maintain immune homeostasis.In recent years, more and more studies have been performed on the involvement of Th 17 and Treg cells in the development and progression of liver diseases .Th17 cells, Treg cells, and their balance may become the new targets for the treatment of NAFLD.This article reviews the latest research advances in the association of Th 17 and Treg cells with NAFLD and the role of Th17/Treg balance in the development and progression of NAFLD .

关键词

非酒精性脂肪性肝病/T淋巴细胞,辅助诱导/T淋巴细胞,调节性/综述

Key words

nonalcoholic fatty liver disease/T -lymphocytes/helper -inducer/T -lymphocytes/regulatory/review

分类

医药卫生

引用本文复制引用

高伟华,葛宽雪,向晓星..辅助性T淋巴细胞17和调节性T淋巴细胞及其平衡改变与非酒精性脂肪性肝病的关系[J].临床肝胆病杂志,2018,34(6):1347-1350,4.

临床肝胆病杂志

OA北大核心CSTPCD

1001-5256

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