安徽医科大学学报2018，Vol.53Issue(2)：254-257,4.DOI:10.19405/j.cnki.issn1000-1492.2018.02.018
慢性肾脏病3-5D期患者血镁浓度与腹主动脉钙化的关系
Study on the relationship between serum magnesium and abdominal aortic calcification in patients with chronic kidney disease
摘要
Abstract
Objective To investigate the relationship between magnesium and abdominal aortic calcification(AAC) in patients with chronic kidney disease (CKD), and then speculate the intervention measures of vascular calcification. Methods 67 cases with CKD3-5D were enrolled in this study and the clinical data were collected. According to the detection of AAC, the patients were divided into calcification group and no calcification group. The factors between two groups were compared and the risk factors of AAC were analyzed. Results There were 15 cases with AAC (22. 4％ ), 52 cases without AAC (77. 6％ ); The age, calcium, phosphorus and calcium phosphorus product in calcified group were significantly higher than those in non calcified group (P < 0. 05); The level of serum magnesium in calcified group was significantly lower than that in non calcified group (2. 2 ± 0. 2 vs 2. 4 ± 0. 4 ) mg/dl(P < 0. 05 ); Gender, the body weight, serum albumin, alkaline phosphatase, intact parathyroid hormone(iPTH), 25 hydroxyvitamin D, cholesterol and triglyceride between the two groups had no significant difference; Two classification Logistic regression analysis showed that age, serum phosphorus, serum magnesium and calcium phosphorus product were the independent risk factors of AAC. The result of magnesium was statistically significant (OR=0.072, 95％ CI: 0. 006 ～0. 836 mg/dl, P =0.035), which were corrected by age, gender, phosphorus, calcium phosphorus product and iPTH. Conclusion Age, high calcium and phosphorus patients prone to abdominal aortic calcification, low magnesium is in addition to age, blood phosphorus and calcium phosphorus products of the abdominal aortic calcification independent risk factors, improving the body s blood magnesium concentration may be conducive to delay the progress of abdominal aortic calcification.关键词
慢性肾脏病/血管钙化/血镁Key words
chronic kidney disease/vascular calcification/serum magnesium分类
医药卫生引用本文复制引用
倪力军,任伟,江洁龙,汪鹏,王科,王丽华,李斌,董行..慢性肾脏病3-5D期患者血镁浓度与腹主动脉钙化的关系[J].安徽医科大学学报,2018,53(2):254-257,4.基金项目
安徽省卫生厅医学科研课题(编号:2010c040) （编号:2010c040）
