安徽医科大学学报2018，Vol.53Issue(3)：453-457,5.DOI:10.19405/j.cnki.issn1000-1492.2018.03.027
腹腔感染患者病原菌分布及耐药性和药敏分析
Distribution, drug resistance and drug sensitivity of pathogens in patients with intra-abdominal infection
摘要
Abstract
Objective To investigate the distribution of pathogens and the results of drug sensitivity test in patients with intra-abdominal infection, and to provide theoretical basis for the rational selection of anti-infective programs. Methods The pathogenic bacteria culture and drug sensitivity test results of peritoneal fluid or drainage fluid in hospitalized patients with intra-abdominal infection were retrospectively analyzed. Results 405 cases of positive culture results were obtained in 3 509 cases of intra-abdominal infection specimens. A total of 436 strains of pathogens, including 268 strains of Gram-negative bacteria (61.47％), 151 strains of Gram-positive bacteria(34. 63％), 17 strains of Fungi (3. 90％). The top five were Escherichia coli (22. 25％), Acinetobacter baumannii (10. 09％), Klebsiella pneumoniae (9. 86％), Enterococcus faecium (7. 80％), Staphylococcus aureus(4. 13％). The extended spectrum β-lactamas rates of Escherichia coli and Klebsiella pneumoniae were 58. 76％ and 16. 28％, respectively. The multi-drug resistant strains of Acinetobacter baumannii were 79. 55％. Vancomycin resistant strains were detected in Enterococcus faecium (8. 82％), the detection rate of methicillin-resistant Staphylococcus aureus (MRSA) in Staphylococcus aureus was 72. 22％, and the detection rate of methicillin-resistant Staphylococcus aureus (MRCNS) in coagulase-negative Staphylococci was 51. 92％. Conclusion The main pathogens of intra-abdominal infection is Escherichia coli, followed by Acinetobacter baumannii, Klebsiella pneumoniae, Enterococcus faecium and Staphylococcus aureus, the detection rate of MRSA and MRCNS is high. The overall drug resistance of intra-abdominal infection is serious.关键词
腹腔感染/病原菌分布/耐药性/药敏Key words
intra-abdominal infection/pathogen distribution/drug resistance/drug sensitivity分类
医药卫生引用本文复制引用
潘剑飞,张泓,戴成才..腹腔感染患者病原菌分布及耐药性和药敏分析[J].安徽医科大学学报,2018,53(3):453-457,5.基金项目
国家临床重点专科建设项目(编号:卫办医政函[2012] 649 号) （编号:卫办医政函[2012] 649 号）
