安徽医科大学学报2018，Vol.53Issue(6)：984-987,4.DOI:10.19405/j.cnki.issn1000-1492.2018.06.034
美菲膜预防中晚期鼻咽癌急性放射性皮肤损伤的疗效观察
Efficacy observation of mepitel film in the prevention of acute radioactive skin injury in advanced nasopharyngeal carcinoma
摘要
Abstract
To observe the efficacy of mepitel film in the prevention of acute radioactive skin injury in advanced na-sopharyngeal carcinoma. One hundred and twenty patients with advanced nasopharyngeal carcinoma who received volumetric modulated arc therapy( VMAT) were randomized divided into mepitel film group,biafine group and con-trol group,40 cases in each group. The occurrence rate,the grade of acute radioactive skin injury and the degree of skin pain in radiation field were assessed. In different irradiation dose,there were statistically significant differences in occurrence rate of acute radioactive skin injury between the mepitel film group and control group(P＜0.05),the differences between the biafine group and control group were statistically significant( P＜0.05) . However, there was no statistically significant differences between the mepitel film and biafine group. After radiotherapy,the grade of acute radioactive skin injury in mepitel film group was lower than biafine group or control group,the differences were statistically significant(P＜0.05). The biafine group was also lower than control group,the differences were statistically significant(P＜0.05). The degree of skin pain in radiation field in mepitel film group was lighter than biafine group or control group,the differences were statistically significant(P＜0.05). The biafine group was also lighter than control group,the differences were statistically significant(P＜0.05). Mepitel film can delay the time of acute radiation skin injury occurrence in patients with advanced nasopharyngeal carcinoma,significantly reduce the grade of acute radioactive skin injury and relieve the degree of skin pain in radiation field.关键词
美菲膜/中晚期鼻咽癌/急性放射性皮肤损伤Key words
mepitel film/advanced nasopharyngeal carcinoma/acute radioactive skin injury分类
医药卫生引用本文复制引用
何健,钱立庭,高劲,陶振超..美菲膜预防中晚期鼻咽癌急性放射性皮肤损伤的疗效观察[J].安徽医科大学学报,2018,53(6):984-987,4.基金项目
安徽省自然科学基金(编号:1408085MH189) （编号:1408085MH189）
安徽省卫生厅医学科研课题(编号:13zc009) （编号:13zc009）
