川北医学院学报2018，Vol.33Issue(3)：334-337,4.DOI:10.3969/j.issn.1005-3697.2018.03.010
扩散加权成像(DWI)在诊断胃肠道恶性肿瘤中的价值
The value of diffusion weighted imaging in diagnosing the gastrointestinal malignant tumors
摘要
Abstract
Objective:To investigate the value of diffusion weighted imaging (DWI) in diagnosing the gastrointestinal malignant tumors. Methods:32 subjects diagnosed gastrointestinal malignant tumors and confirmed by pathology were enrolled,including poorly differentiated gastric adenocarcinoma (18 cases),gastric neuroendocrine carcinoma (7 cases) and gastrointestinal lymphoma (7 ca-ses). 15 volunteers were selected as control group. All the cancer patients and volunteers were performed on MRI,including plain scan-ning and contrast enhanced scanning. The T1WI,T2WI and DWI sequences were selected. The main imaging manifestations were ob-served,the mean signal intensity on T2WI and the ADC values were measured on workstation. The data were analyzed with statistical software. Results:All the tumors showed slightly high signal intensity on T2WI and showed moderate to obvious enhancement after con-trast administration. The mean signal intensity of gastric adenocarcinoma,gastric neuroendocrine carcinoma and gastrointestinal lympho-ma were apparently higher than the normal tissue on T2WI (415. 36 ± 150. 61,408. 67 ± 88. 19,320. 53 ± 63. 37 and 201. 83 ± 45. 92). The difference of signal intensity between the tumors and the normal gastric wall tissue was statistically significant. (P ＜0. 05). All the tumors showed hyperintensity on DWI. The mean ADC values of the adenocarcinoma,neuroendocrine carcinoma,lympho-ma and the normal were (0. 84 ± 0. 15)×10 -3mm2/s,(0. 91 ± 0. 23)×10 -3mm2/s,(1. 25 ± 0. 38)×10 -3mm2/s and (1. 85 ± 0. 36)×10 -3mm2/s,respectively. There was a significant difference between the ADC values of 3 tumor tissues and normal tissues (P＜0. 05). In addition,the statistical significance was also found between adenocarcinoma,neuroendocrine carcinoma,and lymphoma (P＜0. 05),but no statistical significance was also found between adenocarcinoma and neuroendocrine carcinoma (P＞0. 05). Conclu-sion:DWI has potential application value in diagnosis and differentiation of gastrointestinal malignant tumors.关键词
胃肠道恶性肿瘤/扩散加权成像/磁共振成像Key words
Gastrointestinal malignant tumor/Diffusion weighted imaging/Magnetic resonance imaging分类
医药卫生引用本文复制引用
左后东,翟昭华,敬宗林,陈天武..扩散加权成像(DWI)在诊断胃肠道恶性肿瘤中的价值[J].川北医学院学报,2018,33(3):334-337,4.基金项目
国家卫生和计划委员会公益性行业科研专项基金(201402019) （201402019）
体部影像四川省青年科技创新研究团队(2011JTD0030) （2011JTD0030）
