南方医科大学学报2018，Vol.38Issue(6)：647-651,5.DOI:10.3969/j.issn.1673-4254.2018.06.02
一种新的微创胸腔引流管及其兔血胸引流实验
Evaluation of the performance of a minimally invasive thoracic drainage tube in a rabbit model of hemothorax
摘要
Abstract
Objective To assess the performance of a minimally invasive thoracic drainage tube (14 F) made of polyurethane (PU) in a rabbit model of hemothorax in comparison with the conventional 28 F chest tube (CCT).Methods Thirty New Zealand rabbits were divided into experimental chest tube (ECT) group (n=9),CCT group (n=6),and blood provider group (n=15).Blood samples (20 mL) collected from the blood providing rabbits were injected into the chest cavity of the rabbits in the other two groups,and the time taken for closed drainage of the thoracic cavity was recorded.The rabbits in ECT and CCT groups were subjected to blood injections (20 mL for each injection) into the chest cavity every 20 min for 5 times,and the volumes of blood drained by ECT and CCT were measured.Two hours later,the rabbits were sacrificed and the residual blood and blood clots in the chest cavities were observed.Results Compared with CCT,the use of ECT significantly shortened the operation time (P＜0.05) and produced more effective blood drainage at 20 min and 40 min after the placement of the drainage tube (P＜0.05).No significant difference was found in the total blood volume drained between ECT and CCT groups,but the volume of residual blood in the thoracic cavity was significantly smaller in ECT group than in CCT group.No post-operative complications were found in the rabbits in ECT group while all the rabbits in CCT group had abutment pressure to the lung.Conclusion Compared to CCT,ECT is less invasive and allows more effective thoracic drainage with more convenient operation and reduced postoperative complications,suggesting its potential for use in closed thoracic drainage in single-port video-assisted thoracoscopic surgery (VATS) or in pediatric patients.关键词
胸腔引流/胸腔引流管/微创/血胸Key words
chest drainage/chest tube/minimally invasive/hemothorax引用本文复制引用
张家庆,莒瑞红,陈坤棠,阮宝琴,幸婷婷..一种新的微创胸腔引流管及其兔血胸引流实验[J].南方医科大学学报,2018,38(6):647-651,5.基金项目
南方医科大学科技开发培育项目(C1033678) （C1033678）
广东省科技计划(2013B021800156).Supported by Science and Technology Development Project of Southern Medical University (C1033678) and Science and Technology Project of Guangdong Province (2013B021800156). （2013B021800156）
