中国耳鼻咽喉头颈外科2018，Vol.25Issue(2)：61-65,5.DOI:10.16066/j.1672-7002.2018.02.002
右喉返神经后方淋巴结清扫在甲状腺乳头状癌中的临床研究
Clinical research of the lymph node dissection posterior to the right recurrent laryngeal nerve in papillary thyroid carcinoma
摘要
Abstract
OBJECTIVE To investigate the clinical value of the lymph nodes posterior to the right recurrent laryngeal nerve (LN-prRLN, right VI-2) dissection in papillary thyroid carcinoma (PTC). METHODS We studied the relationships between LN-prRLN metastasis and the clinicopathological characteristics in 408 patients with right or bilateral PTC who underwent LN-prRLN dissection. RESULTS Right VI-2 lymph node metastasis was 16.67％. Single factor analysis showed that there were statistically significant correlations between right VI-2 metastasis and gender, age, size and number of right thyroid lobe tumor, capsular invasion, right VI-1 lymph node metastasis and their size, and also metastatic lymph node in the right cervical lateral compartment. Multivariate Logistic regression analysis showed that Right VI-2 lymph node metastasis was related to right tumor size, capsular invasion, the right VI-1 metastasis and right lateral lymph node metastasis(P＜0.05). The receiver-operator characteristic (ROC) analysis showed that the risk factors of LN-prRLN: age ＜35.5 years, right tumor size ＞0.85 cm, lymph node (right VI-1) number ＞1.5, metastatic lymph node (right VI-1) size ＞0.45 cm, lymph node number in the right cervical lateral compartment ＞0.5 and the areas under the ROC curves were 0.585, 0.787, 0.788, 0.725, 0.719. CONCLUSION The dissection of LN-prRLN should be considered when patient with the risk factors such as male, age ＜35.5 years, right tumor size ＞0.85 cm, capsular invasion, lymph node (right VI-1) number ＞1.5, metastatic lymph node (right VI-1) size ＞0.45 cm, lymph node number in the right cervical lateral compartment ＞0.5.关键词
甲状腺肿瘤/危险因素/颈淋巴结清扫术/右喉返神经后方淋巴结Key words
Thyroid Neoplasms/Risk Factors/Neck Dissection/lymph node posterior to the right recurrent laryngeal nerve引用本文复制引用
徐骁诚,丁金旺,彭友,张煜,张卧,潘钢,罗定存..右喉返神经后方淋巴结清扫在甲状腺乳头状癌中的临床研究[J].中国耳鼻咽喉头颈外科,2018,25(2):61-65,5.基金项目
浙江省公益技术应用研究项目(2017C333180)、浙江省医药卫生科技计划项目(2014KYB203)、杭州市医药卫生科技计划项目(2012B004,2013Z04)、杭州市重大科技创新专项项目(20131813A08)和杭州市科技计划项目(20160533B05)联合资助 （2017C333180）
