广西医学2018，Vol.40Issue(11)：1200-1202,1210,4.DOI:10.11675/j.issn.0253-4304.2018.11.13
舒芬太尼对重症冠心病患者冠状动脉旁路移植术后血流动力学的影响
Effects of sufentanil on hemodynamics in patients with severe coronary heart disease after coronary artery bypass grafting
历志 1韩宏光 1徐莉莹 1张晓慧 1孙畅1
作者信息
- 1. 沈阳军区总医院心血管外科,辽宁省沈阳市 110016
- 折叠
摘要
Abstract
Objective To investigate the effects of sufentanil on hemodynamics in the patients with coronary heart disease after coronary artery bypass grafting(CABG). Methods One hundred patients with severe coronary heart disease were randomly divided into observation group(51 cases) and control group(49 cases). Both groups received conventional treatment after CABG,besides,the control group was given sufentanil for analgesia. The hemodynamics changes and the incidence rate of complications after treatment were compared between the two groups. Results Heart rate,central venous pressure(CVP),mean arterial pressure(MAP),cardiac output(CO),systemic vascular resistance index(SVRI) and pulmonary vascular resistance index(PVRI) changed over time(all P＜0. 05). At 12 and 24 hours after treatment,heart rate,SVRI and PVRI were lower and CO was higher in the observation group than those in the control group(all P＜0. 05). At 12 hours after treatment,the level of CVP in the observation group was lower than that in the control group(P＜0. 05). The postoperative duration for mechanical ventilation in the observation group was shorter than that in the control group(P＜0. 05),but there were no significant differences between the two groups in the ICU stay,incidence rate of postoperative acute myocardial infarction,new-onset atrial fibrillation,postoperative ventricular fibrillation or new-onset acute kidney injury,or mortality(all P＞0. 05). Conclusion Sufentanil can improve cardiac function,contribute to stable hemodynamics and reduce the incidence rate of adverse events in the patients with severe coronary heart disease after CABG.关键词
冠心病/冠状动脉旁路移植术/术后/舒芬太尼/血流动力学Key words
Coronary heart disease/Coronary artery bypass grafting/Postoperation/Sufentanil/Hemodynamics分类
医药卫生引用本文复制引用
历志,韩宏光,徐莉莹,张晓慧,孙畅..舒芬太尼对重症冠心病患者冠状动脉旁路移植术后血流动力学的影响[J].广西医学,2018,40(11):1200-1202,1210,4.
