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NGF-TrkA信号通路在胃癌进展和预后中的作用及机制研究

赵会懂 靳海峰

解放军医药杂志2018,Vol.30Issue(6):113-116,4.
解放军医药杂志2018,Vol.30Issue(6):113-116,4.DOI:10.3969/j.issn.2095-140X.2018.06.029

NGF-TrkA信号通路在胃癌进展和预后中的作用及机制研究

Effects and Mechanism of NGF-TrkA Signaling Pathway in Progression and Prognosis of Patients with Gastric Cancer

赵会懂 1靳海峰2

作者信息

  • 1. 050082 石家庄,解放军白求恩国际和平医院编辑部
  • 2. 050082 石家庄,解放军白求恩国际和平医院消化内科
  • 折叠

摘要

Abstract

Nerve infiltration is one of metastatic pathways of gastric cancer, which often induces local recurrence and pain. However, there is still no conclusion about phenomenon of nerve infiltration of gastric cancer and molecular cell mechanism. In recent years, many studies show that nerve growth factor receptor (NGF)-tyrosine protein kinase A (Tr-kA) signaling pathway plays an important role in pathogenesy and development of many kinds of tumors, and therefore a summary of the effects and mechanism of NGF-TrkA signaling pathway in progression and prognosis of gastric cancer has been made.

关键词

NGF-TrkA信号通路/胃肿瘤/预后/神经浸润

Key words

NGF-TrkA signaling pathway/Stomach neoplasms/Prognosis/Nerve infiltration

分类

医药卫生

引用本文复制引用

赵会懂,靳海峰..NGF-TrkA信号通路在胃癌进展和预后中的作用及机制研究[J].解放军医药杂志,2018,30(6):113-116,4.

基金项目

全国优秀博士学位论文作者专项资金资助项目(201363) (201363)

解放军医药杂志

OACSTPCD

2095-140X

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