河北医学2018，Vol.24Issue(6)：987-991,5.DOI:10.3969/j.issn.1006-6233.2018.06.028
美托洛尔联合多巴胺对重症肺炎伴心力衰竭患儿的临床疗效研究
Clinical Efficacy of Metoprolol Combined with Dopamine in Children with Severe Pneumonia Complicated with Heart Failure
摘要
Abstract
Objective: To investigate the clinical efficacy of metoprolol combined with dopamine in the treatment of severe pneumonia complicated with heart failure. Methods: 140 cases of children with severe pneumonia combined with heart failure were selected from June 2015 to December 2016 and randomly divided into the control group and the observation group, 70 cases in each group. Basic supportive therapy and anti-infection treatment, correction of hypovolemia were given to both groups of patients, then equal amount of do-pamine was given to both groups via intravenous drip, the observation group was given oral metoprolol treat-ment on the basis of control group, all the treatment lasted for 7 days. The total effective rate, changes of heart rate, breathing rate and blood oxygen saturation, CK-MB, LDH levels before and after the treatment, im-provement time of clinical symptoms and signs were compared between two groups of patients. Results: After treatment, the total efficiency of observation group (92.86%) was significantly higher than that of the control group (74.29%) (P＝0.00); the heart rate, respiratory rate, serum CK-MB, LDH levels after treatment were significantly lower than those before treatment, which were significantly lower in the observation group than those of the control group ( P＜0.05) ; the blood oxygen saturation of both groups after treatment were sig-nificantly higher than those before treatment, which was significantly higher in the observation group than that of the control group ( P＜0.05) ; the improvement time of symptoms and signs in observation group were shorter than those of the control group( P＜0.05) . Conclusion: Metoprolol combined with dopamine could effectively improve the symptoms and signs, shorten the time of clinical symptoms and signs in the treatment of severe pneumonia with heart failure in children.关键词
美托洛尔/多巴胺/重症肺炎/心力衰竭Key words
Metoprolol/Dopamine/Severe pneumonia/Heart failure引用本文复制引用
廖霓,张国英,熊梓宏,周芹,王孟,赵亚凡,陈应富..美托洛尔联合多巴胺对重症肺炎伴心力衰竭患儿的临床疗效研究[J].河北医学,2018,24(6):987-991,5.基金项目
四川省卫生厅课题,(编号:110064) （编号:110064）
