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首页|期刊导航|河北医学|2型糖尿病肾病患者血清维生素D水平与氧化应激的相关性研究

2型糖尿病肾病患者血清维生素D水平与氧化应激的相关性研究

何建秋 于志伟 李强 高宇 韩桂艳 陈娇月 勾建强

河北医学2018,Vol.24Issue(6):1001-1004,4.
河北医学2018,Vol.24Issue(6):1001-1004,4.DOI:10.3969/j.issn.1006-6233.2018.06.032

2型糖尿病肾病患者血清维生素D水平与氧化应激的相关性研究

Correlation Study of the Levels of Vitamin D with Oxidative Stress in Type 2 Diabetes

何建秋 1于志伟 2李强 3高宇 1韩桂艳 1陈娇月 1勾建强3

作者信息

  • 1. 承德医学院附属医院内分泌科,河北 承德 067000
  • 2. 河北省承德围场满族蒙古族自治县妇幼保健院儿科,河北 围场 068450
  • 3. 河北省承德市中心医院呼吸内科,河北 承德 067000
  • 折叠

摘要

Abstract

Objective: To investigate the correlation of the levels of vitamin D with oxidative stress in type 2 diabetes. Methods:107 cases of patients with type 2 diabetes hospitalized in affiliated hospital of cheng-de medical university were enrolled as objects of the study, the levels of vitamin D、MDA and SOD in the blood were detected. Results: The levels of vitamin D and SOD of contral group, microalbuminuria group and clini-cal proteinuria group were decreased,while the levels of MDA were on the rise, the differences were statistical-ly significant( P<0.05) . The levels of vitamin D and MDA were negtively correlated,and the levels of vitamin D and SOD were positively correlated. Conclusion:The levels of vitamin D and oxidative stress in type 2 dia-betic nephropathy were negtively correlated.

关键词

糖尿病肾病/维生素D/氧化应激

Key words

Diabetic nephropathy/Vitamin D/Oxidative stress

引用本文复制引用

何建秋,于志伟,李强,高宇,韩桂艳,陈娇月,勾建强..2型糖尿病肾病患者血清维生素D水平与氧化应激的相关性研究[J].河北医学,2018,24(6):1001-1004,4.

基金项目

承德市科学技术研究与发展计划项目 (编号:20132046) (编号:20132046)

河北省科技计划项目任务书 (编号:15277755D) (编号:15277755D)

河北医学

OACSTPCD

1006-6233

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