河北医学2018，Vol.24Issue(6)：1025-1028,4.DOI:10.3969/j.issn.1006-6233.2018.06.038
沙丁胺醇布地奈德雾化吸入对毛细支气管炎患儿肺功能的影响
Effects of Nebulization Inhalation of Salbutamol and Budesonide on Pulmonary Function in Children with Bronchiolitis
摘要
Abstract
Objective: To investigate the effects of atomization inhalation of salbutamol and budesonide on pulmonary function in children with bronchiolitis. Methods: A total of 220 children with bronchiolitis hos-pitalized in two families of Langfang Peopleˊs Hospital from November 2013 to November 2016 were selected and divided into the observation group and the control group, with 110 cases in each group. The clinical indi-cators, clinical pulmonary function and curative effect of the two groups were compared. Results: After treat-ment, the observation group was relieved of asthma, cough disappeared, lung rale disappeared and hospitali- zation time, compared with the control group, there were significant differences ( P＜0.05) . Before treatment, there was no significant difference in pulmonary function between the two groups (P ＞ 0.05).After treatment, the Ti /Te(%) 、VPEF /VE(%) 、TPTEF /TE(%) 、Vt /kg( ml/kg) in the observation group was significantly increased with the control group ( P＜0.05) . After treatment in the observation group and the control group, the remarkable effect was (30.91%VS 21.82%); the effective was (56.36%VS 50.00%); the invalid was (12. 73%VS 28.18%); the total effective rate was (87.27%VS 71.82%), there was significant difference(χ2＝10. 208,P＝0.013) . No adverse reaction was found in all two groups. The liver and kidney function and routine hematuria were normal after treatment. Conclusion: 3% hypertonic saline atomization combined with salbuta-mol and budesonide is effective in the treatment of bronchiolitis, significantly improving the lung function of the children, and the safety is better.关键词
毛细支气管炎/沙丁胺醇/布地奈德/肺功能Key words
Bronchiolitis/Albuterol/Budesonide/Lung function引用本文复制引用
于冬辉,刘颖辉,李永红,于丽英..沙丁胺醇布地奈德雾化吸入对毛细支气管炎患儿肺功能的影响[J].河北医学,2018,24(6):1025-1028,4.基金项目
廊坊市科技计划项目,(编号:2016013177) （编号:2016013177）
