湖南中医药大学学报2018，Vol.38Issue(3)：280-283,4.DOI:10.3969/j.issn.1674-070X.2018.03.012
基于肝毒性探讨何首乌临床合理应用
Reasonable Clinical Application of Polygoni Multiflori Radix Based on Hepatotoxicity
摘要
Abstract
Objective To promote rational use of Polygoni Multiflori Radix (Heshouwu) in clinic, to reduce the incidence rate of adverse effects of hepatotoxicity. Methods The potential factors of hepatotoxicity in polygonum multiflorum thunb through consulting document and analysing related experimental data were explored, and then the reasonable clinical use suggestion and the medication guardianship according to the factors were put forward. Results The occurence of hepatotoxicity of Polygoni Multiflori Radix were related to these factors, such as processing method, processing degree, chemical constituents, idiosyncrasy. The quality of drugs, dialectical medication and intensive care for susceptical people should be paid more attention. Conclusion Rational use of Polygoni Multiflori Radix could reduce the incidence rate of hepatotoxicity adverse reactions.关键词
何首乌/肝毒性/合理用药Key words
Polygoni Multiflori Radix/hepatotoxicity/rational drug use分类
医药卫生引用本文复制引用
杨磊,刘梦娇,吴萍,戴冰,张志国..基于肝毒性探讨何首乌临床合理应用[J].湖南中医药大学学报,2018,38(3):280-283,4.基金项目
湖南省自然科学基金(2017JJ3247) （2017JJ3247）
湖南省发改委基金([2016]518). （[2016]518）
