基础医学与临床2018，Vol.38Issue(7)：1020-1024,5.
巨噬细胞自噬在动脉粥样硬化中作用的研究进展
Research progress of macrophage autophagy in atherosclerosis
摘要
Abstract
Autophagy is a self-protecting cell catabolic pathway. That macrophages involved in lipid metabolism dis-orders are the basis of atherosclerotic lesions. Autophagy plays an important role in the inhibition of inflammation and apoptosis and the promotion of cholesterol efflux. The macrophage autophagy can promote lipid metabolism, re-duce the formation of foam cells and inflammation signal, thereby inhibit atherosclerosis. Induction of macrophage autophagy may have potential significance in the treatment of atherosclerosis.关键词
动脉粥样硬化/巨噬细胞/自噬Key words
atherosclerosis/macrophages/autophagy分类
医药卫生引用本文复制引用
密泗宇,周影,王静巧,童茂清,陈晓敏..巨噬细胞自噬在动脉粥样硬化中作用的研究进展[J].基础医学与临床,2018,38(7):1020-1024,5.基金项目
浙江省医药卫生一般研究计划(2016KYB262) （2016KYB262）
宁波市自然科学基金(2014A610269) （2014A610269）
