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肿瘤Notch信号通路的研究进展

王晓清 袁国强 潘亚文

基础医学与临床2018,Vol.38Issue(7):1025-1028,4.
基础医学与临床2018,Vol.38Issue(7):1025-1028,4.

肿瘤Notch信号通路的研究进展

Research progress of Notch signaling pathway in tumor

王晓清 1袁国强 1潘亚文1

作者信息

  • 1. 兰州大学第二医院 神经病学研究所, 甘肃 兰州730030
  • 折叠

摘要

Abstract

Notch gene encodes a class of highly conserved cell surface receptors that determine the fate of cells in embryonic development and mature tissue, which is an important pathway of communication between adjacent cells, and then regulates of cell development, proliferation and apoptosis. The occurrence and progression of multiple tumors are associated with abnormal Notch signaling pathways. For different tumors, it is important significance for anti-tumor therapy to effectively regulate the Notch participants and target molecules.

关键词

Notch信号通路/肿瘤/异常

Key words

Notch signaling pathway/tumor/abnormal

引用本文复制引用

王晓清,袁国强,潘亚文..肿瘤Notch信号通路的研究进展[J].基础医学与临床,2018,38(7):1025-1028,4.

基金项目

兰州市科技项目(2013-3-27) (2013-3-27)

基础医学与临床

OACSCDCSTPCD

1001-6325

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