解放军医学院学报2018，Vol.39Issue(1)：75-77,84,4.DOI:10.3969/j.issn.2095-5227.2018.01.020
PCSK9基因遗传规律与冠心病关系的研究进展
Research advances in relationship between PCSK9 gene polymorphism and coronary heart disease
摘要
Abstract
With the development of molecular biology theory and technology, the relationship between genetic factors and coronary heart disease has become a research hotspot in recent years. The latest study finds that PCSK9 gene is related with coronary heart disease, with different mutations showing different effects on the development of the disease. This theory reveals the causes of racial variation in incidence of coronary heart disease from the perspective of genetics, which indicates the arrival of individualized treatment era of cardiovascular disease and is of great significance to the clinical diagnosis and treatment of this disease. In this paper, the relationship between PCSK9 gene polymorphism and coronary heart disease has been reviewed.关键词
前蛋白转化酶枯草溶菌素9/基因多态性/冠心病Key words
proprotein convertase subtilisin/kexin type 9/gene polymorphism/coronary heart disease分类
医药卫生引用本文复制引用
许嘉彬,王立波,陈伟达..PCSK9基因遗传规律与冠心病关系的研究进展[J].解放军医学院学报,2018,39(1):75-77,84,4.基金项目
黑龙江省自然科学基金项目 (H2016085) （H2016085）
佳木斯大学研究生科技创新项目(YM2016_044) Supported by the Province Natural Science Foundation of Heilongjiang(H2016085) （YM2016_044）
Program of Science Research of Jiamusi University (YM2016_044) （YM2016_044）
