检验医学与临床2018，Vol.15Issue(12)：1727-1729,3.DOI:10.3969／j.issn.1672-9455.2018.12.009
网织红细胞相关参数在新生儿病理性黄疸检测中的意义
The significance of reticulocyte related parameters in the detection of neonatal pathological jaundice
摘要
Abstract
Objective To explore the significance of reticulocyte related parameters in the detection of neo-natal pathological jaundice.Methods A total of 439 cases of neonatal pathological jaundice who treated in hos-pital from January 2012 to December 2016 were enrolled in the study,including 130 cases of hemolytic jaun-dice,96 cases of breast milk jaundice,124 cases of infectious jaundice,89 cases of obstructive jaundice and an-other 100 cases of normal full-term newborns were taken as the full term healthy newborn group.the clinical data were collected,and the related parameters of reticulocyte were determinated.The significance of neonatal pathological jaundice and the correlative parameters of reticulocyte was explored through the analysis of the data.Results The percentage of reticulocyte percentage(RET％)was significantly different between hemo-lytic jaundice group,breast milk jaundice group,infectious jaundice group,obstructive jaundice group,and full-term normal neonatal group(P＜0.01).LSD-t test results showed that the hemolytic jaundice group and the obstructive jaundice group had statistically significant difference compared with the other four groups(P＜0.01).Compare in pairs,there was no significant difference between the groups in the breast milk jaundice group the infectious jaundice group and the full-term normal neonatal group(P＞0.05).The absolute value of reticulocyte(RET#)in the five groups was statistically significant(P＜0.01).According to α＝0.05 level,there was no significant difference between the other four groups in pair comparison except there was a signifi-cant difference between hemolytic jaundice group and the other four groups.The ratio of H-TC％in the 5 groups was statistically significant(P＜0.01),and LSD-t test showed that the differences of hemolytic jaun-dice group,infectious jaundice group and other 4 groups were statistically significant(P＜ 0.01),however there was no significant difference in breast milk jaundice group,obstructive jaundice group and full-term healthy newborn group in pair comparison(P＞0.05).The ratio of RNA in the 5 groups was similar to that in the 5 groups,namely,the hemolytic jaundice group,the infectious jaundice group and the other 4 groups were statistically significant,but there was no statistical significance between the breast milk jaundice group,the obstructive jaundice group and the full term healthy newborn group in pair comparison.The proportion of nu-cleic acid reticulocyte showed similar condition to that of RET #.Conclusion Reticulocyte related parameters have certain clinical significance in the detection of neonatal pathological jaundice.关键词
新生儿/病理性黄疸/网织红细胞参数Key words
new-born/pathological jaundice/parameters of reticulocyte分类
临床医学引用本文复制引用
朱涛,缪丽韶,欧阳能良,黄福达..网织红细胞相关参数在新生儿病理性黄疸检测中的意义[J].检验医学与临床,2018,15(12):1727-1729,3.基金项目
广东省中山市医学科研基金资助项目(2017J046). （2017J046）
