检验医学与临床2018，Vol.15Issue(12)：1803-1805,1868,4.DOI:10.3969／j.issn.1672-9455.2018.12.031
高原地区慢性阻塞性肺疾病患者肺动脉高压发生率及危险因素分析
Prevalence and risk factors of pulmonary hypertension in patients with chronic obstructive pulmonary disease in plateau area
王俊力 1鄢翎 1伍燕 2徐小雅 1师路 3刘蔺1
作者信息
- 1. 航空工业三六三医院呼吸科,成都610041
- 2. 航空工业三六三医院超声科,成都610041
- 3. 航空工业三六三医院胸外科,成都610041
- 折叠
摘要
Abstract
Objective To evaluate the prevalence and potential risk factors of pulmonary hypertension(PH)in patients with chronic obstructive pulmonary disease(COPD)from plateau area.Methods A total of 261 cases of COPD patients from the western Sichuan plateau area who were received in the hospital from Sep-tember 2014 to March 2017 were selected as the research subjects.According to the global initiative of chronic obstructive pulmonary disease(GOLD Guide),92 cases were at GOLD Ⅰ grade,116 cases were at GOLD Ⅱgrade,39 cases were at GOLDⅢ grade,and 14 cases were at GOLDⅣ grade.Routine color Doppler echocardio-graphy was performed.Patients with pulmonary arterial systolic blood pressure(PASP)≥ 40 mm Hg(1 mm Hg＝0.133 kPa)were diagnosed as PH.Results The prevalence of PH was 29.88％.The prevalence of GOLDⅠ grade PH was 19.57％,which was significantly lower 34.48％of GOLDⅡ grade PH and 37.74％of GOLDⅢ － Ⅳ PH,and the differences were statistically significant(P＜0.05).PASP was related to the per-centage(FEV1％),blood oxygen saturation,B type natriuretic peptide,mean platelet volume(MPV),left ven-tricular ejection fraction,and left atrium diameter(r＝ －0.297,－0.303,0.255,0.302,－0.336,0.394,P＜0.05).Logistic regression analysis showed that FEV1％and MPV were risk factors for PH.Conclusion The prevalence of PH is relatively high in COPD patients from plateau area,and patients with lower FEV1％and higher MPV are more likely to have PH.关键词
高原地区/慢性阻塞性肺疾病/肺动脉高压Key words
plateau area/chronic obstructive/pulmonary hypertension分类
医药卫生引用本文复制引用
王俊力,鄢翎,伍燕,徐小雅,师路,刘蔺..高原地区慢性阻塞性肺疾病患者肺动脉高压发生率及危险因素分析[J].检验医学与临床,2018,15(12):1803-1805,1868,4.
