检验医学与临床2018，Vol.15Issue(13)：1869-1871,3.DOI:10.3969/j.issn.1672-9455.2018.13.001
右美托咪定联合舒芬太尼对心脏手术患者麻醉苏醒期心血管应激及躁动的影响
The effect of dexmedetomidine combined with sufentanil on cardiovascular stress and agitation in cardiac surgery
摘要
Abstract
Objective To investigate the effects of dexmedetomidine combined with sufentanil for patients with cardiac surgery anesthesia and cardiovascular stress .Methods The effects of 40 cases of restless heart surgery patients in our hospital during January 2014 to January 2015 were included as an example ,in accord-ance with the principle of randomization ,it can be divided into control group and experimental group .The con-trol group received sufentanil anesthesia ,the experimental group patients received sufentanil combined with dexmedetomidine anesthesia .Observe and evaluate the changes in hemodynamics of two groups of patients during the recovery period of 4 time points and restlessness ,the hemodynamic indexes have systolic blood pressure (SBP) ,heart rate (HR) and pulse oxygen saturation (SpO2).Results Before the end of surgery (T0) there were no significant differences in heart rate and systolic blood pressure in two groups (P＞0 .05) but before tracheal extubation (T1) ,tracheal immediately after the tube (T2) ,5 min after extubation (T3) control of heart rate and systolic pressure groups are lower than those before the end of surgery (T0) were significantly increased ,and significantly .At the same time higher than that of patients in the experimental group (P＜0.05).There were no significant differences in pulse oxygen saturation at four time points in two groups (P＞0 .05).The experimental group patients with restlessness is lower than that of control group (P＜0 .05).Conclusion This study shows that anesthesia for cardiac surgery patients with dexmedetomidine .The drug can be combined with sufentanil ,control of cardiovascular responses during anesthesia recovery period , the extubation process more smoothly and effectively avoid the restlessness of patients in recovery period ,it is worthy of clinical promotion .关键词
心脏手术/右美托咪定/舒芬太尼/心血管应激Key words
cardiac surgery/dexmedetomidine/sufentanil/cardiovascular stress分类
医药卫生引用本文复制引用
李扬,王华,胡颖,刘华..右美托咪定联合舒芬太尼对心脏手术患者麻醉苏醒期心血管应激及躁动的影响[J].检验医学与临床,2018,15(13):1869-1871,3.基金项目
湖北省卫生和计划生育委员会科研资助项目(WJ2017F121) （WJ2017F121）
