检验医学与临床2018，Vol.15Issue(13)：1879-1882,4.DOI:10.3969/j.issn.1672-9455.2018.13.004
七氟醚与瑞芬太尼联用对困难气道患者应激反应、肺功能及血气指标的影响
Effects of sevoflurane combined with remifentanil on stress response ,pulmonary function and blood gas in patients with difficult airway
摘要
Abstract
Objective To investigate the effects of sevoflurane combined with remifentanil on stress re-sponse ,pulmonary function and blood gas analysis in patients with difficult airway .Methods From June 2014 to July 2016 ,90 cases of airway patients with anesthesia were randomly divided into test group and control group and of 45 cases each group .The test group used sevoflurane combined with remifentanil ,and the control group was treated with propofol combined with remifentanil for anesthesia .Comparison of the two groups be-fore and after anesthesia ,intubation after stress response[including blood glucose (GLU) ,cortisol (CRO) , adrenaline (NE) ,adrenaline (NA) ,heart rate (HR) ,mean arterial pressure (MAP) and oxygen saturation (SpO2)] ,pulmonary function (including QS/QT ,pulmonary dynamic compliance ,Ppeak,PETCO2) ,and blood gas index (including PaCO2,PaO2,pH value).Results There are different degrees of fluctuations in the indi-cators in the two groups at the time of T0 ,T1 ,T2 .There were no significant differences in GLU ,CRO ,NA , HR ,MAP ,SpO2,NE ,QS/QT ,pulmonary dynamic compliance ,Ppeak,PETCO2,PaCO2,PaO2 and pH values in the two groups at the time of T0 (P＜0 .05) ,the difference was not statistically significant (P＞0 .05).The PaO2 fluctuation in the experimental group was superior to that in the control group at the time of T1 ,the difference was statistically significant (P＜0 .05).The SpO2 fluctuation of the experimental group was better than that of the control group at the time of T2 ,the difference was statistically significant (P＜0 .05).GLU , CRO ,NA ,HR ,MAP ,NE ,pulmonary dynamic compliance and Ppeak fluctuation of the experimental group were better than those of the control group at the time of T1 ,T2 ,the difference was statistically significant (P＜0 .05).Conclusion Combination of sevoflurane and remifentanil can significantly improve the stress response in patients with difficult airway ,lung function and the impact of blood gas analysis of patients ,it is worth pro-moting .关键词
七氟醚/困难气道/应激反应/肺功能/血气指标Key words
sevoflurane/difficult airway/stress response/pulmonary function/blood gas index分类
医药卫生引用本文复制引用
胡颖..七氟醚与瑞芬太尼联用对困难气道患者应激反应、肺功能及血气指标的影响[J].检验医学与临床,2018,15(13):1879-1882,4.基金项目
湖北省卫生和计划生育委员会科研资助项目(WJ2017F125) （WJ2017F125）
湖北省教育厅重点项目(D20171902) （D20171902）
