检验医学与临床2018，Vol.15Issue(13)：1883-1884,1888,3.DOI:10.3969/j.issn.1672-9455.2018.13.005
血清VCA-IgA、NA1-IgA、Zta-IgA检测在鼻咽癌筛查中的应用价值
Application value of VCA-IgA,NA1-IgA and Zta-IgA detection in screening of nasopharyngeal carcinoma
摘要
Abstract
Objective To investigate the application value of VCA-IgA ,NA1-IgA ,Zta-IgA detection in the screening of nasopharyngeal carcinoma .Methods A total of 100 cases of nasopharyngeal carcinoma patients treated in our hospital from February 2010 to April 2016 were selected as the observation group ,and all of them were confirmed by pathology ;And 500 cases of non carcinoma diagnosed with nasopharyngeal symptoms in the same period were selected as control group ;Enzyme linked immunosorbent assay (ELISA) was used to detect the positive rates of serum VCA-IgA ,NA1-IgA and Zta-IgA in the three groups .Results The positive rates of serum VCA-IgA ,NA1-IgA and Zta-IgA were significantly different between two groups (EB) (P＜0 .05).The results of combined diagnosis were higher than those of single diagnosis .The sensitivity and specific-ity of diagnosis were above 90.0%,and the positive predictive rate was 69.6% .Conclusion The combined detection of three kinds of antibodies against EB virus is of great value in the early diagnosis of nasopharyngeal carcinoma .关键词
鼻咽癌/EB病毒壳抗原免疫球蛋白A/EB病毒核抗原1免疫球蛋白A/Zta蛋白抗体免疫球蛋白AKey words
nasopharyngeal carcinoma/EB virus shell antigen immunoglobulin A/EB virus nuclear an-tigen 1 immunoglobulin A/Zta protein antibody immunoglobulin A分类
医药卫生引用本文复制引用
陈善昌,吴家恩,张小娟,陈栋,胡静云,彭凌..血清VCA-IgA、NA1-IgA、Zta-IgA检测在鼻咽癌筛查中的应用价值[J].检验医学与临床,2018,15(13):1883-1884,1888,3.基金项目
广西壮族自治区贺州市科学研究与技术开发计划(贺科转1503012) （贺科转1503012）
