摘要
Abstract
Objective To analyze the effect factors on quality of life of perimenopausal women with hyper-thyroidism .Methods From December 2011 to December 2016 ,153 perimenopausal women with hyperthyroid-ism in our hospital were divided into high score group (WHOQOL-BREF score≥ 80) and low score group (WHOQOL-BREF score＜ 80).The related effect factors of menopausal women with hyperthyroidism were analyzed with single factor χ2 test and multivariate Logistic method .Results The WHOQOL-BREF score of 153 patients was from 24 to 108 points ,with an average of (79 .4 ± 10 .5)points .There were 62 cases in high score group (40 .5%) and 91 cases in low score group (59 .5%).Univariate analysis showed that the rate of patients with FT4≥60 pmol/L in low score group was 62 .6%,higher than 33 .9% in high score group .The rate of divorced or widowed patients in low score group was 31 .9%,higher than 8 .1% in high score group (χ2＝3 .963 ,P＝0 .047).The rate of patients with culture of junior high school and below in low score group was 91 .2%,higher than 75 .8% in high score group (χ2＝8 .184 ,P＝0 .004).The rate of patients with family monthly income ＜2 000 yuan in low score group was 52 .7%,higher than 32 .3% in high score group (χ2＝6 .270 ,P＝0 .012).The rate of patients with family discord in low score group was 41 .8%,higher than 17 .7% in high score group (χ2＝9 .770 ,P＝0 .002).The rate of patients with long term consumption of soy products in low score group was 56 .0%,lower than 72 .6% in high score group (χ2＝4 .314 ,P＝0 .038).The rate of pa-tients with other diseases in low score group was 84 .6%,higher than 53 .2% in high score group(χ2＝17 .982 , P＝ 0.000).These differences were statistically significant (P＜ 0 .05).Multivariate analysis showed that FT4≥60 pmol/L (OR＝3 .659 ,95% CI :1 .246 －9 .231 ,P＝0 .002) ,divorced or widowed (OR＝2 .144 ,95%CI :1 .173－4 .234 ,P＝0 .027) ,family monthly income＜2 000 yuan(OR＝2 .235 ,95% CI :1 .023 －5 .776 ,P＝0 .033) ,family discord(OR＝1 .813 ,95% CI :1 .272 －3 .995 ,P＝0 .045) ,combined with other diseases (OR＝3 .179 ,95% CI :1 .142－8 .579 ,P＝0 .011) were the main risk factors of low quality of life in perimenopausal women with hyperthyroidism ,and long term consumption of soy products (OR＝ 0 .417 ,95% CI :0 .102 －0 .876 ,P＝0 .024) was the protective factor (P＜0 .05).Conclusion The level of quality of life of perimenopa-usal women with hyperthyroidism is low .Divorced or widowed ,family monthly income ＜2 000 yuan ,family discord ,combined with other diseases are the main risk factors ,long term consumption of soy products is the protective factor .So we should strengthen the treatment and control of hyperthyroidism and other related dis-eases ,give full family care and psychological support ,guide to increase consumption of soy products ,to im-prove the quality of life .关键词
甲状腺功能亢进/围绝经期/生活质量Key words
perimenopausal period/hyperthyroidism/quality of life分类
医药卫生
