摘要
Abstract
Objective To investigate the correlation between the change of vaginal microenvironment and high-risk human papillomavirus (HR-HPV) infection .Methods From January 2016 to May 2017 ,2 945 pa-tients with negative cytology of cervix in Tangxia gynecology clinic of Dongguan hospital were selected ,and the correlation between the change of vaginal microenvironment and HR-HPV infection was analyzed . Results There were 1 957 cases of vaginal micro environment change in 2 945 cases ,accounting for 66 .45% . Aerobic vaginitis (AV) accounted for 302 cases (15 .43%) ,bacterial vaginosis (BV) accounted for 578 cases (29 .54%) ,vulvovaginal candidiasis (VVC) accounted for 276 cases (14 .10%) ,trichomonas vaginitis (TV) accounted for 225 cases (11 .50%) ,pure hydrogen peroxide (H2O2) deficiency accounted for 246 cases (12 .57%) simple ,H2O2 and white blood cell lipase (LE) was 330 cases (16 .86%) ,mixed vaginitis accounted for 439 cases (22 .43%) ,and HR-HPV infection were 78 cases (25 .83%) ,184 cases (31 .86%) ,83 cases (30 .11%) ,56 cases (24 .92%) ,62 cases (25 .24%) ,94 cases (28 .48%) ,215 cases (48 .97%) ;each group a-bove and the vaginal microenvironment of normal group (normal group) HR-HPV infection rate was statisti-cally significant (P＜0 .05) ;BV ,VVC and other types of vaginal micro environment change was statistically significant (P＜0 .05).Differences of infection rates of AV ,TV and other types of vaginal micro environment change patients had no statistically significance (P＞0 .05) ;mixed vaginitis and HR-HPV infection rate were statistically significance (P＜0 .05).Conclusion AV ,BV ,VVC ,the TV ,H2O2,H2O2 and simple lack of pure LE positive were correlated with HR-HPV infection .关键词
阴道微环境/人乳头瘤病毒感染/宫颈癌Key words
vaginal microenvironment/human papilloma virus infection/cervical cancer分类
临床医学
