昆明医科大学学报2018,Vol.39Issue(5):61-65,5.
昆明地区小儿社区获得性下呼吸道感染病原菌分析
Etiological Analysis of Community-acquired Lower Respiratory Tract Infection in Children in Kunming
摘要
Abstract
Objective To investigate epidemiological characteristics of pathogenic bacteria of community-acquired lower respiratory tract infection in children in Kunming (with an altitude of 1860 m) . Methods The results of bacterial culture of 9793 patients with community-acquired lower respiratory tract infection in the Second Affiliated Hospital of Kunming Medical University and Kunming Maternal and Child Health Hospital from Jan 2011 to Nov 2015 were reviewed.Results Among the 9793 phlegm samples from the children patients with community-acquired lower respiratory tract infection, 8433 (86.10%) phlegm samples were qualified, 2 918 (34.6%) had a positive bacterial culture.The pathogenic bacteria mainly were gram-negative bacteria (1 839 strains, 58.9%), and gram-positive bacteria (1 284 strains, 41.4%) . The detection rate of gram-negative bacteria was increasing, among which Haemophilus was in a leading position (768 strains, 24.60%),followed by Streptococcus pneumonia (665 strains, 21.3%),E. coli (315 strains, 10.10%), Staphylococcus aureus (310 strains, 9.9%), Moraxella catarrhalis (272 strains, 8.7%), and Klebsiella pneumoniae bacillus (224 strains, 7.2%) . The detection rates of six common bacteria in different seasons were significantly different (P<0.05) . The detection rates of six common bacteria except Moraxella catarrhalis in different age groups were significantly different (P<0.05) . Conclusions Gram-negative bacterium was the main pathogenic bacteria for those children who got community-acquired lower respiratory tract infections. Haemophilus influenza was the most common pathogenic bacteria and the detection rate of pathogenic bacteria in winter was high. The most common pathogenic bacteria in infants and toddler were Haemophilus influenza. The most common pathogen in preschool and school-age children was Streptococcus pneumonia.The pathogenic bacteria of lower respiratory tract infection in the children community of Kunming are different from those in the plain area.关键词
社区获得性下呼吸道感染/病原菌/小儿Key words
Community-acquired lower respiratory tract infection/Pathogenic Bacteria/Children分类
医药卫生引用本文复制引用
赵琳,曹丽云,吕高洁,李明盼..昆明地区小儿社区获得性下呼吸道感染病原菌分析[J].昆明医科大学学报,2018,39(5):61-65,5.基金项目
云南省医疗卫生单位内设研究机构科研基金资助项目(2014NS082) (2014NS082)