口腔颌面外科杂志2017，Vol.27Issue(4)：272-274,3.DOI:10.3969/j.issn.1005-4979.2017.04.009
两种预防性抗生素使用方法在正颌手术中的应用比较
Perioperative Antibiotic Prophylaxis in Orthognathic Surgery: a Clinical Trial
孙浩云 1吴中兴 1杨学文1
作者信息
- 1. 武汉大学口腔医院正颌整形外科,口腔生物医学工程重点实验室,湖北 武汉 430079
- 折叠
摘要
Abstract
Objective: The purpose of this study was to evaluate the efficacy of antibiotic prophylaxis in orthognathic surgery between different methods and conclude a proper one. Methods: To retrospectively analyze the infection results of selected 60 patients in orthognathic surgery, from April 2015 to April 2016. According to the hospitalization date and the application of antibiotics, the patients were divided into 2 groups. In group A, the period of hospitalization were from April 2015 to October 2015, and the postoperative antibiotics application lasted for 7 days until discharged. In group B, the period of hospitalization were from October 2015 to April 2016, and each patient intravenously received a single-dose of first generation cephalosporin 30 minutes before surgery, and one dose of antibiotics administered every 8 hours until 48 hours postoperation. Patients' temperature, purulent drainage, pain or tenderness, local swelling, and wound healing were recorded and compared. Results: There was no postoperative infection happened in both groups. Conclusion: It is suggest-ed that the first dose antibiotics given 30 mins before surgery and continued for two days is more economic, safe and effective.关键词
正颌外科手术/抗生素/预防性用药/术后感染Key words
orthognathic surgery/application of antibiotics/prophylaxis/surgical site infection分类
医药卫生引用本文复制引用
孙浩云,吴中兴,杨学文..两种预防性抗生素使用方法在正颌手术中的应用比较[J].口腔颌面外科杂志,2017,27(4):272-274,3.
