临床与实验病理学杂志2018，Vol.34Issue(1)：55-59,5.DOI:10.13315/j.cnki.cjcep.2018.01.013
胎盘间叶发育不良5例临床病理分析
Clinicopathological analysis of 5 cases of placental mesenchymal dysplasia
摘要
Abstract
Purpose To explore the clinicopathological features, diagnosis, differential diagnosis and prognosis of placental mesenchymal dysplasia. Method The clinicopathological data of 5 cases with placental mesenchymal dysplasia were retrospectively analysed and related literatures were also re-viewed. Results All of 5 patients were consciously fetal movement disappeared or found abnormal ultrasound results at routine examination of the pregnancy. The placentas were enlarged, partly with oedematous "grape-like" cysts. On histologic exami-nation, enlarged villi with varying degrees of edema contained abnormal thick walled fetal blood vessels. The chorionic vessels were expanded and congested, and some chorionic villi showed mesenchymal cell hyperplasia. In immunohistochemical staining, p57 was positive, and Ki-67 showed low expression. There was no the trophoblastic proliferation. It's mainly differential diagnosis was hydatidiform mole.2 cases were accompanied with stillbirth. Conclusion The diagnosis of placental mesenchymal dysplasia can be confirmed by pathology examination. When a cystic placenta is detected by ultrasound examination, placental mesenchymal dysplasia should be considered in the differential diagnosis.关键词
胎盘间叶发育不良/绒毛水肿/非葡萄胎妊娠/鉴别诊断Key words
placental mesenchymal dysplasia/villous edema/non-hydatidiform pregnancy/differential diagnosis分类
医药卫生引用本文复制引用
詹阳,郑兴征,阴赪宏,谷玉春,朱力..胎盘间叶发育不良5例临床病理分析[J].临床与实验病理学杂志,2018,34(1):55-59,5.基金项目
北京市属医院科研培育计划(PX2016070) （PX2016070）
