中国临床保健杂志2018,Vol.21Issue(3):289-292,4.DOI:10.3969/J.issn.1672-6790.2018.03.001
高龄老人亚临床甲状腺功能减退对颈动脉易损斑块的影响
Effect of subclinical hypothyroidism on the vulnerable carotid artery plaque in the advanced-ages
摘要
Abstract
Objective To observe the effect of subclinical hypothyroidism (SCH) on the vulnerable carotid ar-tery plaque in the advanced-ages .Methods This study was performed on 118 elderly patients with age over 80,inclu-ding 78 cases with normal thyroid function and 40 cases with SCH.Characteristics of carotid plaque of these patients were evaluated by ultrasound.The detection rate of vulnerable carotid artery plaque and the level of blood glucose ,lipid, uric acid of the two groups were compared.Logistic regression was used to analyze the risk factors of vulnerable carotid artery plaque.Results The detection rate of vulnerable carotid artery plaque in SCH group was 52.5%,where as in normal thyroid function groupwas 30.8%.There was significantly difference between them (χ2=5.292,P=0.028).Lo-gistic regression showed that the vulnerable carotid artery plaque was related to significantly subclinical hypothyroidism and total cholesterol in the advanced-ages (P<0.05).Conclusion Subclinical hypothyroidism and the increase of to-tal cholesterol are associated with vulnerable carotid artery plaque.Screening of thyroid function and the cotroll of lipid should be focused in the advanced-ages.关键词
亚临床甲状腺功能减退/颈动脉/斑块,动脉粥样硬化/易损斑块Key words
Subclinical hypothyroidism/Carotid artery/Plaque,atherosclerotic/Vulnerable plaque分类
医药卫生引用本文复制引用
荣荣,任安,胡立群,尹长森,张世阳,张梦媛..高龄老人亚临床甲状腺功能减退对颈动脉易损斑块的影响[J].中国临床保健杂志,2018,21(3):289-292,4.基金项目
安徽省年度科研计划项目(10021303013 ) (10021303013 )