中国临床保健杂志2018，Vol.21Issue(3)：345-348,4.DOI:10.3969/J.issn.1672－6790.2018.03.016
糖化血红蛋白水平对急性 ST段抬高型心肌梗死患者住院期间及近期预后的影响
Influence of glycosylated hemoglobin level on in－hospital and short－term prognosis of patients with STEMI
程昭栋 1杨体霞 1周利民 1张军 1王三刚 1李峰1
作者信息
- 1. 安徽滁州市第一人民医院心血管内科,239000
- 折叠
摘要
Abstract
Objective To evaluate the influence of glycosylated hemoglobin (HbA1c) level on in－hospital and 30 days prognosis of patients with ST－elevation myocardial infarction (STEMI).Methods 121cases of diagnosed STE－MI by coronary angiography were divided into two groups according to the level of glycosylated hemoglobin :higher glyco－sylated hemoglobin group(n＝51) and normal glycosylated hemoglobin group (n＝70).Glycosylated hemoglobin level, coronary angiography,the peak of troponin concentration,the peak value of plasma brain natriuretic peptide(BNP),main adverse cardiac events(MACE),hospitalization time and LVEF of 30 days post－discharge were measured and recorded. Influence of glycosylated hemoglobin level on in－hospital and short－term prognosis of patients with STEMI were analyzed according to the index above.Results Higher glycosylated hemoglobin group had significant higher incidence rate com － pared with the normal glycosylated hemoglobin group in the double branch lesions and three branch lesions in the pa －tients with STEMI(P＜0.05).Significant difference was found between normal glycosylated hemoglobin group and high －er glycosylated hemoglobin group in the incidence of localized stenosis ( P ＜0.05).Higher glycosylated hemoglobin group was significantly higher than in normal glycosylated hemoglobin group in the incidence of diffused stenosis ( P＜0.05).Significant difference was found between normal glycosylated hemoglobin group and higher glycosylated hemoglo －bin group on the BNP peak and LVEF of 30 days(P＜0.05).In comparison,the higher glycosylated hemoglobin group had longer hospital stay than normal glycosylated hemoglobin group (P＜0.05).There were no significant difference be－tween normal glycosylated hemoglobin group and higher glycosylated hemoglobin group in the peak of troponin concentra －tion and MACE(P＞0.05).Conclusions Elevated HbA1c level is an important factor leading to complex coronary ar－tery lesions,and can lead to the deterioration of heart function with prolonged hospitalization time ,thereby affecting the short－term prognosis in patients with STEMI.关键词
心肌梗死/糖化血红蛋白/预后Key words
Myocardial infarction/Glycosylated hemoglobin/Prognosis分类
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程昭栋,杨体霞,周利民,张军,王三刚,李峰..糖化血红蛋白水平对急性 ST段抬高型心肌梗死患者住院期间及近期预后的影响[J].中国临床保健杂志,2018,21(3):345-348,4.
