中国临床保健杂志2018,Vol.21Issue(3):419-422,4.DOI:10.3969/J.issn.1672-6790.2018.03.034
γδT 细胞在恶性肿瘤治疗中的作用及其研究进展
The role of γδT-cell in the treatment of malignant tumor and research progress
摘要
Abstract
γδT cell antigen recognition does not require specific antigen stimulation withou MHC restriction , thus it has a natural and adaptive immune response in the anti-tumor immunity.Activation of γδT cells exert cytotoxic effect on tumor cells through various ways which has the potential to serve as a powerful tool in tumor immunotherapy .A large number of studies have shown that γδT cells have good antitumor effect in vitro and in vivo.As a new tumor immu-notherapy,γδT cell immunotherapy technology shows a promising application prospect .This article will focus on the role of γδT cells in the treatment of malignant tumors and their research progress.关键词
肿瘤/免疫疗法/T淋巴细胞Key words
Neoplasms/Immunotherapy/T-lymphocytes分类
医药卫生引用本文复制引用
谢蕾,程民,胡世莲,沈干..γδT 细胞在恶性肿瘤治疗中的作用及其研究进展[J].中国临床保健杂志,2018,21(3):419-422,4.基金项目
国家自然科学基金面上项目(81471552) (81471552)
安徽省科技攻关项目(1501041142 ) (1501041142 )
肿瘤免疫与营养治疗安徽省重点实验室绩效项目(1606c08236) (1606c08236)