摘要
Abstract
Objective To analyze and investigate the postoperative complications and related factors of transarterial inter-ventional therapy and endoscopic submucosal dissection(ESD)in the treatment of early gastric cancer,and to provide references and ideas for the treatment and prognosis of early gastric cancer. Methods A total of 65 patients with early gastric cancer admitted to our hospital from July 2014 to December 2016 were selected as study subjects and divided into control group(n=31)and obser-vation group(n=34). The control group was treated with ESD alone,while the observation group was given transarterial interven-tion combined with ESD. The success rate of operation and the occurrence of postoperative complications were observed and ana-lyzed,and the related factors that lead to complications were analyzed. Results The total effective rate of patients with combined transarterial chemotherapy and ESD therapy was slightly better than that of patients treated with ESD alone,and the hospitalization time was also shorter,but the difference was not statistically significant(P＞0. 05);The scores of quality of life in patients with combined therapy were higher,statistically significant(P＜0. 05);Combined therapy significantly increased the incidence of post-operative complications,and the difference was statistically significant(P＜0. 05). There was no significant difference in the inci-dence of postoperative infection,perforation,delayed hemorrhage and abnormal function of important organs(heart,liver,kidney) between the control group and the observation group(P＞0. 05);The rate of digestive tract reaction in the observation group was significantly higher than that in the control group(P＜0. 05). Conclusions The overall efficacy of combined therapy in the treat-ment of early gastric cancer is slightly better than that of ESD alone. However,combined therapy can cause a higher rate of postop-erative complications. Combination therapy does not reduce the rate of complications such as perforation and hemorrhage in ESD, but the gastrointestinal reaction in combination therapy is significantly increased,which deserves attention in clinical treatment.关键词
胃癌/胃动脉介入/内镜黏膜下剥离术/术后并发症Key words
gastric cancer/gastric artery intervention/endoscopic submucosal dissection/postoperative complications分类
医药卫生
