四川医学2018，Vol.39Issue(6)：669-673,5.DOI:10.16252/j.cnki.issn1004-0501-2018.06.018
老年急性髓系白血病临床及预后分析
Analysis of Clinical and Prognosis of Elderly Acute Myeloid Leukemia
姜涛 1万纯黔 1陈姣 1黄娟 1肖蓉 1李成龙 1李慧 1黄晓兵1
作者信息
- 1. 四川省医学科学院·四川省人民医院血液科,四川 成都610072
- 折叠
摘要
Abstract
Objective To investigate the clinical,prognosis and related risk factors of elderly acute myeloid leukemia. Methods The clinical and laboratory data of elderly patients with acute myeloid leukemia diagnosed in our hospital from 2007 to 2016 were retrospectively analyzed. Univariate and multivariate analyses of prognostic factors were performed using a Cox regression model. Results 209 patients were divided into standard treatment group,low-dose chemotherapy group and supportive treatment group. The median survival time was 26 months,19 months and 4 months respectively. High-risk karyotypes and/or genetic abnor-malities,CCI more than or equal to 2 and high leukocytes are independent adverse risk factors affecting prognosis. Conclusion Chemotherapy can still improve prognosis and prolong survival of elderly patients with acute myeloid leukemia(AML)Patients with high-risk karyotypes and/or genetic abnormalities,high CCI scores and high leukocytes have a poor prognosis.关键词
急性髓系白血病/合并症评分/预后Key words
acute myeloid leukemia/comorbidity score/prognosis分类
医药卫生引用本文复制引用
姜涛,万纯黔,陈姣,黄娟,肖蓉,李成龙,李慧,黄晓兵..老年急性髓系白血病临床及预后分析[J].四川医学,2018,39(6):669-673,5.
