四川医学2018，Vol.39Issue(6)：686-689,4.DOI:10.16252/j.cnki.issn1004-0501-2018.06.022
重复经颅磁刺激治疗精神分裂症顽固性幻听的效果及作用机制分析
Effect and Mechanism of Repeated Transcranial Magnetic Stimulation in the Treatment of Intractable Auditory Hal-lucinations in Schizophrenia
李彬 1黎润仪 1许锦冰 1汤超华 1郑广恩1
作者信息
- 1. 佛山市第三人民医院精神科,广东 佛山528000
- 折叠
摘要
Abstract
Objective To investigate the effect and mechanism of repetitive transcranial magnetic stimulation( rTMS) in the treatment of intractable auditory hallucinations in schizophrenia. Methods From February 2016 to November 2017,126 pa-tients with intractable hearing hallucinations of schizophrenia treated in our hospital were selected and randomly divided into two groups. Patients in the control group were treated with pseudo stimulation,while the patients in the trial group were given rTMS. The differences of AHRS,CGI,PSYRATS,SAS and PANSS between the two groups were observed and compared. Results After treat-ment,the AHRS score of the patients in the trial group was(4. 51 ± 1. 25),and the CGI score was(4. 07 ± 1. 32),significantly lower than those in the control group(P＜0. 05);In the test group,the PSYRATS score was(14. 64 ± 2. 15),and the SAS score was(30. 86 ± 4. 07),significantly lower than those in the control group(P＜0. 05);After treatment,the scores of auditory halluci-nations,positive symptoms,negative symptoms and the general condition analysis were(2. 93 ± 0. 97),(16. 93 ± 3. 62),(12. 99 ± 3. 58)and(23. 01 ± 3. 53) respectively in the experimental group,which were significantly improved compared with the control group(P＜0. 05). Conclusion rTMS therapy can relieve the symptoms of schizophrenia,improve the symptoms of auditory hallu-cinations and relieve the bad emotions,which is worth popularizing.关键词
rTMS/精神分裂症/顽固性幻听/作用机制Key words
rTMS/Schizophrenia/obstinate auditory hallucinations/mechanism of action分类
医药卫生引用本文复制引用
李彬,黎润仪,许锦冰,汤超华,郑广恩..重复经颅磁刺激治疗精神分裂症顽固性幻听的效果及作用机制分析[J].四川医学,2018,39(6):686-689,4.
