同济大学学报（医学版）2018，Vol.39Issue(3)：84-88,93,6.DOI:10.16118/j.1008-0392.2018.03.016
侵袭性垂体瘤致颈内动脉海绵窦段移位的研究
Intracavernous internal carotid artery displacement caused by invasive pituitary adenoma
摘要
Abstract
Objective To explore the effect of invasive pituitary adenoma at different stages on the cavernous segment displacement of internal carotid artery. Methods The distance between the bilateral intracavernous internal carotid artery segment in median were measured in MRI images; the differences among the invasive pituitary adenoma, non-saddle region lesions and subgroups of invasive pituitary adenoma were analyzed. Results The distance of bilateral internal carotid artery segment in Knosp classification grade 0,Ⅰ,Ⅱ,Ⅲ,Ⅳinvasive pituitary adenomas and non-saddle lesion ( control group) were 15. 64, 18. 63, 24. 05, 29. 13 and 30. 05 mm, respectively. There was no significant difference between the control group and the grade 0 subgroup of pituitary adenoma ( P＝0. 179) ; while there were significant differences between the control group and grade Ⅰ,Ⅱ,Ⅲ,Ⅳ of invasive pituitary adenomas ( P＜0. 001) , between grade 0 and grade Ⅰ,Ⅱ,Ⅲ,Ⅳ subgroups of pituitary adenomas ( P＜0. 001) , between grade Ⅰ and grade Ⅱ,Ⅲ,Ⅳ( P＜0. 001) , between grade Ⅱ and grade Ⅲ,Ⅳ( P＜0. 001 ) ; however, there was no significant difference between grade Ⅲ and grade Ⅳsubgroups ( P ＝ 0. 680 ). Conclusion Invasive pituitary adenoma can cause displacement of the intracavernous internal carotid artery, the displacement is correlated with the Knosp grading. In transsphenoidal approach the attention should be paid to the shift of the intracavernous internal carotid artery caused by the invasive pituitary adenoma.关键词
侵袭性垂体瘤/颈内动脉海绵窦段/Knosp分级/海绵窦/垂体腺瘤Key words
invasive pituitary adenoma/cavernous segment internal carotid artery/cavernous sinus/Knosp classification/pituitary adenoma分类
医药卫生引用本文复制引用
黄山,张义,李士其,王涛,李文纲..侵袭性垂体瘤致颈内动脉海绵窦段移位的研究[J].同济大学学报（医学版）,2018,39(3):84-88,93,6.基金项目
复旦大学附属上海市第五人民医院院级青年基金(2010WYQJ01) （2010WYQJ01）
上海市闵行区自然科学研究基金(2009MHZ113) （2009MHZ113）
