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结直肠癌患者血清SOD水平与营养状况关系的临床研究

申颖 吴萍 陈莹 罗斌

同济大学学报(医学版)2018,Vol.39Issue(3):94-98,5.
同济大学学报(医学版)2018,Vol.39Issue(3):94-98,5.DOI:10.16118/j.1008-0392.2018.03.018

结直肠癌患者血清SOD水平与营养状况关系的临床研究

Relationship between serum SOD level and nutritional status in patients with colorectal cancer

申颖 1吴萍 1陈莹 2罗斌1

作者信息

  • 1. 同济大学附属同济医院临床营养科,上海 200065
  • 2. 同济大学附属同济医院消化内科,上海 200065
  • 折叠

摘要

Abstract

Objective To analyze the relationship between serum SOD level and nutritional status in colorectal cancer patients.Methods Clinical data of 136 patients with colorectal cancer and 63 patients with gastrointestinal polyps treated in Tongji Hospital from May 2013 to July 2017 were retrospective reviewed. The relationship between serum SOD level and nutritional indicators ( total protein, albumin, prealbumin, hemoglobin and lymphocyte count) in two groups was analyzed with SPSS 21. 0 statistical software. Results The levels of serum SOD, albumin, hemoglobin and lymphocytes in patients with gastrointestinal polyps were higher than those in colorectal cancer patients ( P<0. 05). Serum SOD levels in patients with colorectal cancer without distant metastasis were higher than those in patients with distant metastases ( P<0. 05 ). Serum SOD level was positively correlated with total protein, albumin, prealbumin, hemoglobin and lymphocyte count in colorectal cancer patients ( P<0. 05 ). Conclusion Serum SOD levels are positively correlated with the nutritional status of colorectal cancer patients. And lower serum SOD level and nutritional status may indicate the distant metastasis in colorectal cancer.

关键词

结直肠癌/超氧化物歧化酶/营养状况

Key words

colorectal cancer/superoxide dismutase/nutritional status

分类

医药卫生

引用本文复制引用

申颖,吴萍,陈莹,罗斌..结直肠癌患者血清SOD水平与营养状况关系的临床研究[J].同济大学学报(医学版),2018,39(3):94-98,5.

基金项目

国家自然基金青年项目(81502041) (81502041)

同济大学学报(医学版)

OACSTPCD

1008-0392

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