世界中医药2018，Vol.13Issue(6)：1428-1431,4.DOI:10.3969/j.issn.1673-7202.2018.06.029
四妙丸加减对痛风性关节炎的治疗效果及对实验室指标的影响
Clinical Efficacy of Simiao Pills Addition and Subtraction on Gouty Arthritis and Its Influence on Laboratory Indexes
摘要
Abstract
Objective:To explore the effect of simiao pills addition and subtraction on gouty arthritis and its influence on laboratory indexes.Methods:A total of 98 patients with gouty arthritis treated in our hospital were acted as the study objectives ,and were di－vided into the observation group and the control group ,according to the random digital table method ,each group with 49 cases.The control group was treated with conventional western medicine ,and observation group was treated with simiao pills addition and sub－traction on the basis of the control group ,and 2 groups were treated for 1 month continuously.The clinical efficacy of 2 groups was statisticsed and the traditional Chinese medicine (TCM) syndrome scores and related laboratory indexes of 2 groups were compared before and after treatment.Results:The total effective rate of observation group was 89.80%,which was significantly higher than the 79.59%of control group ( P＜0.05); compared with that before treatment.TCM syndrome scores of 2 groups such as joint pain,swelling,redness,joint function limitation and systemic symptoms significantly decreased after treatment (P＜0.01),and ob－servation group was significantly lower than control group (P＜0.05 or P＜0.01); compared with before treatment,the serum IL－6,IL－8,CRP,TNF－αand the whole blood BUA,ESR and WBC levels of 2 groups decreased after treatment (P＜0.01),and obser－vation group was significantly lower than control group (P＜0.05 or P＜0.01).Conclusion:Simiao pills addition and subtraction in the treatment of gouty arthritis can reduce the levels of inflammatory factors and related laboratory indexes ,significantly alleviate the joint symptoms of the patients ,and the clinical effect is better than that of western medicine alone.关键词
痛风性关节炎/四妙丸加减/效果/实验室指标Key words
Gouty arthritis/Simiao pills addition and subtraction/Effect/Laboratory index分类
医药卫生引用本文复制引用
刘亚梅,刘建梅..四妙丸加减对痛风性关节炎的治疗效果及对实验室指标的影响[J].世界中医药,2018,13(6):1428-1431,4.基金项目
陕西省科技计划资助项目(2013K12－14－03) （2013K12－14－03）
