世界中医药2018，Vol.13Issue(6)：1541-1545,5.DOI:10.3969/j.issn.1673-7202.2018.06.056
陕产瞿麦中总黄酮提取工艺响应曲面法的优化
Study on Optimization of Total Flavonoids of Herba Dianthi from Shaanxi in the Extraction Process by Response Surface Method
摘要
Abstract
Objective:To select the optimized plan of ultrasonic assisted extracting total flavonoids in Herba Dianthi from Shaanxi by the response surface method.Methods:In this experiment, Shaanxi producing Herba Dianthi was taken as raw material , and ethanol as extraction agent.On the basis of single factor experiment , the extraction process of total flavonoids from Herba Dianthi of Shaanxi by ultrasonic assisted method was optimized with the response surface method .Results:The ultrasonic assisted extraction conditions of total flavonoids in Herba Dianthi from Shaanxi were optimized :liquid and material ratio was 10 times, extraction pow－er 140W, 80%ethanol concentration , and the extraction rate of flavonoids could reach 0.851%.Conclusion:The process of the experimental values are basically consistent with the predicted value , indicating using response surface methodology to optimize ul－trasonic assisted extraction technology of flavonoids in Herba Dianthi in Shaanxi Province is stable and feasible , and providing ref－erence for the development and utilization of Herba dianthi resources in Shaanxi Province.关键词
陕产瞿麦/黄酮类化合物/超声提取/响应曲面法/单因素试验/紫外可见分光光度法/工艺条件/提取率Key words
Herba Dianthi in Shaanxi Province/Flavonoids/Ultrasonic extraction/Response surface method/Single factor test/UV visible spectrophotometry/Process conditions/Extraction rate分类
医药卫生引用本文复制引用
张爽,刘治飞,高洁,问娟娟..陕产瞿麦中总黄酮提取工艺响应曲面法的优化[J].世界中医药,2018,13(6):1541-1545,5.基金项目
陕西省教育厅2017年专项科学研究计划(17JK0944) （17JK0944）
2016年陕西省大学生创新创业训练计划项目(2955) （2955）
陕西国际商贸学院校级科研课题(SMXY201629) （SMXY201629）
