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射频热凝联合阿霉素用于原发性三叉神经痛治疗的临床研究

杨茂林 梁琳 范向凯

山西医科大学学报2018,Vol.49Issue(6):678-681,4.
山西医科大学学报2018,Vol.49Issue(6):678-681,4.DOI:10.13753/j.issn.1007-6611.2018.06.019

射频热凝联合阿霉素用于原发性三叉神经痛治疗的临床研究

Clinical study of radiofrequency thermocoagulation combined with pirarubicin in the treatment of idiopathic trigeminal neu-ralgia

杨茂林 1梁琳 2范向凯2

作者信息

  • 1. 三亚市人民医院疼痛科,三亚 572000
  • 2. 晋城市人民医院疼痛科
  • 折叠

摘要

Abstract

Objective To evaluate the efficacy and safety of radiofrequency thermocoagulation(RFT)combined with pirarubicin in the treatment of idiopathic trigeminal neuralgia. Methods Ninety patients with idiopathic trigeminal neuralgia after failure by conservative treatment were randomly divided into three groups(n=30):pirarubicin alone group,radiofrequency thermocoagulation(RFT)com-bined with pirarubicin group,and radiofrequency thermocoagulation group. VAS score,two-year relapse rate and complications were compared among three groups at different time points. Results The VAS score in combination group was significantly lower than in pirarubicin group 1 d,7 d,14 d,after treatment(P<0. 05). There was no significant difference in VAS score between the three groups at 1 month,6 months and one year after treatment. The relapse rate was significantly lower in combination group than in the other two groups 2 years after treatment. There were no significant complications in the three groups. Conclusion Radiofrequency thermo-coagulation(RFT)combined with pirarubicin is effective in the treatment of trigeminal neuralgia with better short-term and long-term effect,and it is worthy of clinical application.

关键词

原发性三叉神经痛/射频热凝/阿霉素

Key words

idiopathic trigeminal neuralgia/radiofrequency thermocoagulation/pirarubicin

分类

医药卫生

引用本文复制引用

杨茂林,梁琳,范向凯..射频热凝联合阿霉素用于原发性三叉神经痛治疗的临床研究[J].山西医科大学学报,2018,49(6):678-681,4.

山西医科大学学报

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1007-6611

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