实用医学杂志2018，Vol.34Issue(12)：2004-2006,2011,4.DOI:10.3969/j.issn.1006-5725.2018.12.020
3D腹腔镜Glisson蒂横断式肝切除术治疗肝癌对机体细胞免疫功能的影响
Effect of 3D laparoscopic hepatectomy in glissonian approach for hepatocellular carcinoma on the cellular immune function
摘要
Abstract
Objective To compare the effects of 3D laparoscopic hepatectomy (3D-LH) and open hepatectomy(OH)in glissonian access for hepatocellular carcinoma(HCC)on postoperative immunosuppression by analyzing cellular immune function. Methods During January 2014 to December 2017,sixty patients randomly scheduled to undergo hepatectomy were divided into 3D-LH group and OH group,with 30 patients in each group. All patients' peripheral blood was sampled to measure cell-mediated-immunologic markers(CD4+,CD8+T cell) before operation and in the mornings of the 1st,7thday after surgery. The effects of different operative methods on cellular immune function in patients organism were investigated. Results The decreased level in 3D-LH group was less than that in OH group in postoperative 1stday. The improvement in the 3D-LH group was more faster than that in the OH group on postoperative 7thday. There was statistical significance between the two groups(P<0.05), respectively. Conclusion When compared to open hepatectomy ,3D laparoscopy liver resection in glissonian approach for HCC,less effects in cellular immune function.关键词
肝癌/ 3D腹腔镜/细胞免疫功能/格里森蒂/肝切除术Key words
hepatocellular carcinoma/3 D laparoscopy/cellular immune function/glissonian/liver resection引用本文复制引用
方兆山,杨剑,庞珏,刘文瑛,张智,阮婕,黄海..3D腹腔镜Glisson蒂横断式肝切除术治疗肝癌对机体细胞免疫功能的影响[J].实用医学杂志,2018,34(12):2004-2006,2011,4.基金项目
广东省公益研究与能力建设专项(编号:2016A02 0220013) （编号:2016A02 0220013）
国家自然科学基金青年基金项目(编号:81601576) （编号:81601576）
广州市产学研协同创新重大专项(编号:201704020141) （编号:201704020141）
南宁市普通外科腔镜微创中心建设项目(编号:20153012) （编号:20153012）
南宁市科技局攻关计划项目(编号:20143173) （编号:20143173）
