生殖医学杂志2018，Vol.27Issue(7)：623-626,4.DOI:10.3969/j.issn.1004-3845.2018.07.004
雌激素在不明原因薄型子宫内膜治疗中的应用
Application of estrogen in treatment of unexplained thin endometrium
刘艳红 1王霞 1王爱华 1李燕 1牛英会1
作者信息
- 1. 河北省邯郸市妇幼保健院生殖医学科,邯郸 056001
- 折叠
摘要
Abstract
Objective:To investigate the application of estrogen in unexplained thin endometrium. Methods: Ninety six patients with unexplained thin endometrium were treated with small dose of aspirin combined with estrogen in our hospital from Jan.2014 to Jun.2016.According to the random number table,the patients were divided into 3 groups and given different estrogen preparations:oral progynova grop,femonston oral grop,femonston vaginal administration group,32 patients in each group.The endometrial thickness,type,blood flow,blood estradiol(E2)concentration and pregnancy rate were compared before and after treatment among the three groups. Results: The endometrial thickness,type,and blood flow were significantly improved after drug treatment(P＜0.05),and serum E2levels and clinical pregnancy rate were also significantly higher than before treatment in the patients with unexplained thin endometrium(P＜0.05).The endometrial thickness in femonston vaginal administration group [(9.02±0.23)mm],E2levels [(1 853.5±255.8)pmol/L]and the pregnancy rate(53.13%)were significantly higher than those in oral progynova group [(7.80±0.95)mm, (1 201.4±198.4)pmol/L,25.00%,respectively]and femonston oral group [(8.04±0.43)mm,(1 395.3± 203.3)pmol/L,28.13%,respectively](P＜0.05). Conclusions:Aspirin combined with estrogen treatment for the patients with unexplained thin endometrium can get satisfactory results.However,a large sample of prospective studies is still needed to verify.关键词
薄型子宫内膜/雌激素/内膜厚度/临床妊娠Key words
Thin endometrium/Estrodiol/Endometrial thickness/Clinical pregnancy引用本文复制引用
刘艳红,王霞,王爱华,李燕,牛英会..雌激素在不明原因薄型子宫内膜治疗中的应用[J].生殖医学杂志,2018,27(7):623-626,4.
