生殖医学杂志2018，Vol.27Issue(7)：662-665,4.DOI:10.3969/j.issn.1004-3845.2018.07.012
肥胖及超重不孕妇女抗精子抗体的评价
Evaluation of antisperm antibody in infertile women with obesity or overweight
摘要
Abstract
Objective:To investigate the level of the serum antisperm antibody(ASA)in infertile women with obesity or overweight to clarify whether ASA mediates the decline in fertility of such infertile women. Methods: A total of 190 infertile women aged 26-35 years were divided into 3 groups according to the body mass index(BMI):group A(BMI≤24;n=90),group B(24＜BMI＜28;n=62)and group C(BMI≥28;n=38).The ASA type IgG and IgA in serum were screened by the indirect immunobead test according to the WHO laboratory manual.50% or more of motile sperm adherence to the immunoglobulin was regarded as clinical positivity;20% to 49% motile was sub-positive;Less than 20% was negative. Results:One case was detected to be ASA-IgG positive (1.1 %)in group A.No case showed the clinical positive level in groups B and C.Two cases(2.2%)in group A,1 case in group B(1.6%)and 1 case (2.6 %)in group C were ASA-IgG sub-positive,and the sub-positive incidence was not significantly different among the three groups(P＞0.05).ASA-IgA was not detected in all the three groups. Conclusions:ASA is not associated with the etiology of infertile women with obesity or overweight.关键词
肥胖/超重/女性不孕/抗精子抗体Key words
Obesity/Overweight/Female infertility/Antisperm antibody引用本文复制引用
江欢,李晓红,朱伟杰..肥胖及超重不孕妇女抗精子抗体的评价[J].生殖医学杂志,2018,27(7):662-665,4.基金项目
广东省科技计划项目(2014A020213007) （2014A020213007）
