天津中医药2018，Vol.35Issue(7)：512-516,5.DOI:10.11656/j.issn.1672-1519.2018.07.11
三九胃泰制剂治疗慢性胃炎疗效与安全性的系统评价
Systematic review on effect and safety of Sanjiu Weitai for chronic gastritis
摘要
Abstract
[Objective] In this study, we evaluated the efficacy and safety of Sanjiu Weitai for chronic gastritis. [Methods] We searched CNKI, Wanfang Data, SinoMed and PubMed (before Sep 2016), and collected relevant randomized controlled trials (RCTs). Two authors independently performed screening the literature and data extraction, the quality of included references was evaluated according to criteria recommended by Cochrane Handbook and the disputes were resolved through discussion. [Results] A total of 673 articles were retrieved and 8 RCTs, including 614 patients were enrolled in this study according to the inclusion criteria. Because of a significant clinical heterogeneity among these studies, we finally performed descriptive analysis instead of data analysis. Sanjiu Weitai showed comparative efficacy in alleviating clinical symptoms including abdominal pain, belching, acid regurgitation and etc., compared to omeprazole, teprenone, bismuth potassium citrate granule, marzulene-S and antibiotics. In the clearance rate of Hp, the efficacy of Sanjiu Weitai is not so good as bismuth potassium citrate granule, but in restoring intestinal metaplasia and gastric mucosal hyperplasia, Sanjiu Weitai has a comparative efficacy with marzulene-S. When concerned with safety, no obvious adverse reactions were reported in the group of Sanjiu Weitai. [Conclusion] Sanjiu Weitai was effective for Chronic Gastritis. However, due to the limited number of eligible RCTs, significant heterogeneity and poor methodological quality, the advantages of Sanjiu Weitai in treating chronic gastritis need high quality RCTs to prove.关键词
三九胃泰/慢性胃炎/疗效/安全性/系统评价Key words
Sanjiu Weitai/chronic gastritis/effect/safety/systematic review分类
医药卫生引用本文复制引用
邹佳涵,杨丰文,李雪梅..三九胃泰制剂治疗慢性胃炎疗效与安全性的系统评价[J].天津中医药,2018,35(7):512-516,5.基金项目
国家自然科学基金项目(81473544) （81473544）
天津市人才发展特殊支持计划 ——青年拔尖人才项目(201504). （201504）
