西安交通大学学报（医学版）2018，Vol.39Issue(4)：455-458,4.DOI:10.7652/jdyxb201804001
冠心病血管内皮损伤与血管重构的研究进展
Advances in research on the mechanism of vascular endothelial injury and vascular remodeling in coronary atherosclerosis
摘要
Abstract
Vascular endothelial injury is the initial manifestation of coronary atherosclerosis,and currently there are many researches on the mechanism of vascular endothelial injury.If the risk factors for coronary athero-sclerotic heart disease (CAD)are sustained and not reversed,endothelial dysfunction will occur,followed by coro-nary remodeling,and ultimately will lead to the occurrence of CAD.The study on the mechanism of vascular endo-thelial injury and vascular remodeling plays an important role in predicting the development of CAD and guiding the treatment of CAD.Percutaneous coronary intervention (PCI)is one of the main revascularizations for coronary heart disease.With the evolution of drug-eluting stents,the incidence of thrombosis and restenosis caused by vascu-lar endothelial injury after PCI is reduced.Biocompatibility of coronary stent technology is also improved based on the mechanism of vascular endothelial dysfunction and vascular remodeling.关键词
血管内皮损伤/冠状动脉粥样硬化/血管重构/血运重建/经皮冠状动脉介入术Key words
vascular endothelial injury/coronary atherosclerosis/vascular remodeling/coronary revasculariza-tion/percutaneous coronary intervention分类
医药卫生引用本文复制引用
王聪霞,范雅洁..冠心病血管内皮损伤与血管重构的研究进展[J].西安交通大学学报（医学版）,2018,39(4):455-458,4.基金项目
国家自然科学基金资助项目(No.81273878).Supported by the National Natural Science Foundation of China (No.81273878) （No.81273878）
