中国医疗设备2018，Vol.33Issue(7)：44-47,4.DOI:10.3969/j.issn.1674-1633.2018.07.011
DBS术前图像与ICBM-152图谱的配准算法
Registration Algorithm of DBS Preoperative Image and ICBM-152 Atlas
摘要
Abstract
Deep brain stimulation (DBS) surgical treatment is an important treatment for patients with Parkinson's disease. One of the effective ways of preoperative navigation and nuclei identification for DBS is to perform registration between brain atlases and preoperative images. In this paper, we initially implemented the registration of preoperative images and ICBM-152 atlas. We firstly normalized the preoperative clinical image to the coordinate space of the atlas, and then used piecewise linear registration to coarsely map the spectrum, at last, non-rigid registration of the brain atlas with preoperative data was achieved using mutual information as a measure of similarity. Thereby a personalized brain atlas could be calculated for each patient, the experimental results showed that the mutual information between the image and the atlas was 0.558 in the initial stage of the experiment, while it increased to 1.217 when the proposed method was employed.关键词
脑图谱/帕金森病/脑深部电刺激手术/配准Key words
brain atlas/Parkinson's disease/deep brain stimulation/registration分类
信息技术与安全科学引用本文复制引用
倪杨阳,郑慧芬,曹胜武,罗守华..DBS术前图像与ICBM-152图谱的配准算法[J].中国医疗设备,2018,33(7):44-47,4.基金项目
国家重点研发计划(2017YFA0104302) （2017YFA0104302）
东南大学苏州纳米技术协同创新中心的支持. （）
