疑难病杂志2018，Vol.17Issue(7)：729-731,3.DOI:10.3969/j.issn.1671-6450.2018.07.019
涎腺类乳腺分泌性癌8例临床病理分析
Mammary analogue secretary carcinoma of salivary glands: case report and clinicopathological analysis
摘要
Abstract
Objective To investigate the clinicopathological features, diagnosis, differential diagnosis of mammary analogue secretary carcinoma of salivary glands ( MASC). Methods The clinicopathological features, immunohistochemical technology, diagnosis, differential diagnosis of eight MASC cases were analyzed retrospectively. Results All the investigated MASC patients were treated with painless mass as the first symptom. Among these 8 cases,4 cases occurred in the right parotid region,3 cases occurred in the left parotid region. 1 case occurred in the palate. Postoperative pathological examination was consistent with MASC. The immunophenotype of 8 cases of tumor cells were as follows: S 100,vimentin and CK7 were all pos-itive in 8 cases,mammaglobin was positive in 7 of 8 cases,only one case of CK protein expression was positive. The patients had been followed up for 15～64 months,6 cases were found with no tumor survival,local recurrence in one case,there was no distant metastasis,one case died of other diseases. Conclusion MASC is a malignant tumor with a characteristic of breast se-cretory carcinoma occurring in salivary glands. The diagnosis mainly depends on postoperative pathological examination and immunophenotype, combined with genetic examination is helpful for diagnosis.关键词
涎腺肿瘤/分泌性癌/临床病理特点Key words
Salivary gland neoplasms/Mammary analogue secretory carcinoma/Clinicopathological features引用本文复制引用
张金莲,蔡兆根,吴琼,秦燕子,王梦慧,董修芹,欧玉荣..涎腺类乳腺分泌性癌8例临床病理分析[J].疑难病杂志,2018,17(7):729-731,3.基金项目
安徽省教育厅自然科学基金重点项目(KJ2016A468) （KJ2016A468）
