应用化学2018，Vol.35Issue(5)：532-537,6.DOI:10.11944/j.issn.1000-0518.2018.05.170197
一种香豆素类锌离子荧光探针的合成及性能
Synthesis and Properties of a Zn2+ Fluorescent Probe Based on Coumarins
摘要
Abstract
A coumarin type fluorescent probe was synthesized from 1H-indole-3-carbohydrazide hydrazide and 8-formyl 7-hydroxy-4-methylcoumarin,which was obtained by Pechmann condensation of resorcinol and ethyl acetoacetate followed by formylation employing hexamethylenetetramine.The structure and fluorescence properties of this probe were characterized by nuclear magnetic resonance spectroscopy(NMR),mass spectrometry(MS),fluorescence emission spectrometer and UV-visible absorption spectrum.The probe coordinated with Zn2+in 1:1 ratio and led to high selectivity for the detection of Zn2+with a detection limit at 3.6×10-8 mol/L.These demonstrate potential application of the probe for the detection of Zn2+in biological studies.关键词
香豆素/荧光探针/锌离子/吲哚酰肼Key words
coumarin/fluorescent probe/zinc ion/indole hydrazide分类
化学化工引用本文复制引用
苏策,常开善,李思良,李冠斌,张红博,白玲玲..一种香豆素类锌离子荧光探针的合成及性能[J].应用化学,2018,35(5):532-537,6.基金项目
国家自然科学基金(21462025)资助 Supported by the National Natural Science Foundation Project(No.21462025) （21462025）
