中国肺癌杂志2018，Vol.21Issue(6)：458-462,5.DOI:10.3779/j.issn.1009-3419.2018.06.06
胸腔注射榄香烯致严重不良反应7例病例系列分析
Severe Adverse Reactions Induced by the Chest Injection of Elemene:An Analysis of 7 Cases
高菲 1邵宜 1钟殿胜 1刘夏 1孟凡路1
作者信息
- 1. 300052 天津,天津医科大学总医院肿瘤科
- 折叠
摘要
Abstract
Background and objective Malignant pleural effusion (MPE) refers to pleural effusion which arises from primary malignant tumor of pleura or other pleural metastatic tumors. Injection of elemene in chest makes good effect on the treatment of MPE, and is widely used in clinic. Adverse effects also exist, but the severe adverse effects and relevant manage-ments are rarely reported. The aim of this study is to observe the adverse reactions induced by the treatment of malignant pleu-ral effusion through elemene injection and to explore the solutions. Methods A retrospective analysis was made on 14 cases of patients receiving intra-pleural injections with elemene, and the incidence of severe adverse reactions of 7 cases were disscussed in detail. Results Most of the severe adverse reactions caused by elemene were severe chest pain, dyspnea, wheezing, clouding of consciousness and coagulopathy. Conclusion Strict screening, full preprocessing and close monitoring are necessary to pre-vent serious adverse reactions caused by elemene injection in the treatment of malignant pleural effusion.关键词
榄香烯注射液/胸腔注射/不良反应/恶性胸腔积液/呼吸困难Key words
Elemene injection/Chest injection/Adverse reactions/Malignant pleural effusion/Dyspnea引用本文复制引用
高菲,邵宜,钟殿胜,刘夏,孟凡路..胸腔注射榄香烯致严重不良反应7例病例系列分析[J].中国肺癌杂志,2018,21(6):458-462,5.
