中国肺癌杂志2018，Vol.21Issue(6)：463-469,7.DOI:10.3779/j.issn.1009-3419.2018.06.07
临床Ia期肺腺癌N分期上调的危险因素
Risk Factors of Nodal Upstaging in Clinical Ia Lung Adenocarcinoma
秦毅 1邱桐 1玄云鹏 1赵艳东 1矫文捷1
作者信息
- 1. 266001 青岛,青岛大学附属医院胸外科
- 折叠
摘要
Abstract
Background and objective In clinical Ia (cT1N0M0) patients, some may have poor prognosis, for it might occur pathologic N1 (pN1) or N2 (pN2) postoperatively. The aim of this study is to determine the radio-logicaland pathological factors related to clinical Ia adenocarcinoma. Methods The retrospective study was conducted on 297 clinical Ia adenocarcinoma patients resected at our hospital between May 2012 to December 2016. The clinical profiles, radiological and pathological features were analyzed between nodal upstaging group and non-upstaging group. Results Of 297 patients treated for cN0 tumors, 250 cases (84.2%) were confirmed postoperatively as having pN0 tumors, and 47 (15.8%) were confirmed as having pN1 or pN2 tumors. Female, low smoking index, micropapillary pre-dominant and solid predominant adenocarcinoma, puresolid tumor and large tumor size were all more frequently seen in the nodal upstaging group than in the pN0 group (P＜0.05). Logistic regression indicate that radiological solid tumor, micropapillary predominant and solid predominant adenocarcinoma and vessel invasionare the risk factors of nodal upstaging in clinical Ia adenocarcinoma. Conclusion Radiological solid tumors, micropapillary predominant and solid predominant adenocarcinoma andvessel invasion are risk factors for nodal upstaging for early stage lung cancer. Radio-logical solid tumors should perform SLND in Ia adenocarcinomas.关键词
肺肿瘤/临床早期/N分期/影像学/病理学Key words
Lung neoplasms/Clinical early stage/N upstaging/Radiology/Pathology引用本文复制引用
秦毅,邱桐,玄云鹏,赵艳东,矫文捷..临床Ia期肺腺癌N分期上调的危险因素[J].中国肺癌杂志,2018,21(6):463-469,7.
