中国光学2018，Vol.11Issue(3)：475-502,28.DOI:10.3788/CO.20181103.0475
长周期光栅生物传感器研究进展
Research progress of biosensors based on long period fiber grating
摘要
Abstract
Long period fiber grating is a kind of passive optical device which is sensitive to the surrounding en -vironment.Owing to without retroreflection , high sensitivity to refractive index , miniature size, easy integra-tion, immunity to electromagnetic interference , non-corrosiveness, without the need of reference electrode , long period fiber grating based optical sensors have attracted much attention in the field of refractive index sensing.Since Bentley research group first used long period fiber gratings to detect antigens in 2000, long-pe-riod gratings have made great progress in the detection of biological substances in recent years and have been utilized for the detection of many biological substances such as antigen-antibody , bacterial viruses , proteins, DNA, enzymes, nucleic acids, and so on.In this paper, the research progress and applications of long period fiber grating in the biosensing field in recent years are summarized and reviewed , and the future development trend of long period fiber grating in biological detection is also prospected .关键词
长周期光栅/生物技术/检测/传感器/进展Key words
long period fiber grating/biotechnology/detection/sensor/progress分类
信息技术与安全科学引用本文复制引用
李秋顺,蔡雷,马耀宏,杨俊慧,杨艳,孟庆军,史建国..长周期光栅生物传感器研究进展[J].中国光学,2018,11(3):475-502,28.基金项目
国家自然科学基金项目(No.61340032,No.61535010,No.31500858) （No.61340032,No.61535010,No.31500858）
山东省自然科学基金项目(No. ZR2012CM029) （No. ZR2012CM029）
山东省重点研发计划项目( No.2016ZDJS07A20) （ No.2016ZDJS07A20）
山东省科学院青年基金项目( No. 2017QN0010) （ No. 2017QN0010）
国家高技术研究发展计划(863计划)资助项目(No.2015AA021005)Supported by National Natural Science Foundation of China (No.61340032, No.61535010, No.31500858) （863计划）
Natural Science Foundation of Shandong Province ( No.ZR2012CM029) （ No.ZR2012CM029）
Research Development Program of Shandong Province(No.2016ZDJS07A20) （No.2016ZDJS07A20）
Youth Fund of Shandong Academy of Sciences (No.2017QN0010) （No.2017QN0010）
the National High Technology Research and Development Program of China (No.2015AA021005) （No.2015AA021005）
