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远隔缺血后适应治疗对缺血性脑卒中患者神经功能保护作用的临床研究

王心颖 丁文婷 鲍双振 高倩 魏琰 崔永健

中国全科医学2018,Vol.21Issue(18):2163-2166,4.
中国全科医学2018,Vol.21Issue(18):2163-2166,4.DOI:10.3969/j.issn.1007-9572.2018.00.193

远隔缺血后适应治疗对缺血性脑卒中患者神经功能保护作用的临床研究

Remote Ischemic Postconditioning for Improving the Neurological Function of Patients with Ischemic Stroke

王心颖 1丁文婷 1鲍双振 2高倩 1魏琰 1崔永健1

作者信息

  • 1. 053000河北省衡水市,哈励逊国际和平医院神经内科
  • 2. 053000河北省衡水市,哈励逊国际和平医院普外科
  • 折叠

摘要

Abstract

Objective To investigate the effect of remote ischemic postconditioning(IP) on the improvement of neurological function of patients with ischemic stroke.Methods We enrolled 200 cases of ischemic stroke from Department of Neurology,Harrison International Peace Hospital in Hengshui between January 2016 and June 2017.Using random number table,we divided them into the experimental group(n=100) receiving basic drug treatment combined with IP and control group(n=100) receiving basic drug treatment alone.The National Institutes of Health Stroke Scale (NIHSS) scores and the incidence of lateralization were recorded in the two groups before and 12 months after treatment.Results The NIHSS score was similar in both groups before treatment(P>0.05),but it was significantly decreased in the experimental group after 12-month treatment〔(13.3±2.1)scores vs. (15.2±1.8)scores〕(P<0.05).There was no significant difference in the incidence of lateralization between the two groups before treatment (P>0.05),and the incidence of lateralization in the experimental group was higher than that of the control group after 12 months of treatment(P<0.05).Conclusion IP could significantly improve the neurological function and promote the development of collaterals in the cerebral circulation,which is worth popularizing in clinical practice.

关键词

卒中/脑缺血/远隔缺血后适应/神经功能

Key words

Stroke/Brain ischemia/Remote ischemic preconditioning/Neurological function

分类

医药卫生

引用本文复制引用

王心颖,丁文婷,鲍双振,高倩,魏琰,崔永健..远隔缺血后适应治疗对缺血性脑卒中患者神经功能保护作用的临床研究[J].中国全科医学,2018,21(18):2163-2166,4.

基金项目

2016年衡水市科技计划项目(2016014115Z) (2016014115Z)

中国全科医学

OA北大核心CSTPCD

1007-9572

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