中国全科医学2018,Vol.21Issue(18):2163-2166,4.DOI:10.3969/j.issn.1007-9572.2018.00.193
远隔缺血后适应治疗对缺血性脑卒中患者神经功能保护作用的临床研究
Remote Ischemic Postconditioning for Improving the Neurological Function of Patients with Ischemic Stroke
摘要
Abstract
Objective To investigate the effect of remote ischemic postconditioning(IP) on the improvement of neurological function of patients with ischemic stroke.Methods We enrolled 200 cases of ischemic stroke from Department of Neurology,Harrison International Peace Hospital in Hengshui between January 2016 and June 2017.Using random number table,we divided them into the experimental group(n=100) receiving basic drug treatment combined with IP and control group(n=100) receiving basic drug treatment alone.The National Institutes of Health Stroke Scale (NIHSS) scores and the incidence of lateralization were recorded in the two groups before and 12 months after treatment.Results The NIHSS score was similar in both groups before treatment(P>0.05),but it was significantly decreased in the experimental group after 12-month treatment〔(13.3±2.1)scores vs. (15.2±1.8)scores〕(P<0.05).There was no significant difference in the incidence of lateralization between the two groups before treatment (P>0.05),and the incidence of lateralization in the experimental group was higher than that of the control group after 12 months of treatment(P<0.05).Conclusion IP could significantly improve the neurological function and promote the development of collaterals in the cerebral circulation,which is worth popularizing in clinical practice.关键词
卒中/脑缺血/远隔缺血后适应/神经功能Key words
Stroke/Brain ischemia/Remote ischemic preconditioning/Neurological function分类
医药卫生引用本文复制引用
王心颖,丁文婷,鲍双振,高倩,魏琰,崔永健..远隔缺血后适应治疗对缺血性脑卒中患者神经功能保护作用的临床研究[J].中国全科医学,2018,21(18):2163-2166,4.基金项目
2016年衡水市科技计划项目(2016014115Z) (2016014115Z)